Publication Name	World Journal of Orthopedics
Manuscript ID	75180
Country	India

Received	2022-01-17 19:06
Peer-Review Started	2022-01-17 19:06
To Make the First Decision
Return for Revision	2022-02-21 07:32
Revised	2022-03-02 12:42
Second Decision	2022-08-22 03:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-08-25 20:59
Articles in Press	2022-08-25 20:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-09-04 08:30
Publish the Manuscript Online	2022-09-16 12:55

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Case Control Study
Article Title	Histological difference in ligament flavum between degenerative lumbar canal stenosis and non-stenotic group: A prospective, comparative study
Manuscript Source	Invited Manuscript
All Author List	Mantu Jain, Mukund Sable, Amit Purushottam Tirpude, Rabi Narayan Sahu, Sudeep Kumar Samanta and Gurudip Das
ORCID	Author(s) ORCID Number Mantu Jain http://orcid.org/0000-0003-3848-4277 Mukund Sable http://orcid.org/0000-0002-5364-1464 Amit Purushottam Tirpude http://orcid.org/0000-0003-0223-2270 Rabi Narayan Sahu http://orcid.org/0000-0003-1429-2123 Sudeep Kumar Samanta http://orcid.org/0000-0003-3543-4485 Gurudip Das http://orcid.org/0000-0001-7887-5526
Funding Agency and Grant Number
Corresponding Author	Mantu Jain, MD, Doctor, Surgeon, Department of Orthopaedics, All India Institute of Medical Sciences Bhubaneswar, Bhuabneswar 751019, Odisha, India. montu_jn@yahoo.com
Key Words	Spinal stenosis; Lumbar spine; Ligamentum flavum; histopathology; Morphometry
Core Tip	The ligament flavum (LF) is vital in the pathogenesis of lumbar canal stenosis (LCS). The purely elastic LF undergoes a morphological adaptation that includes a reduction in the elastic fibers with a consequent increase in the collagen content, fibrosis, cicatrization, and calcification. The present study provides a detailed morphometric analysis to semiquantitatively delineate the LF changes in patients with LCS from those in patients without LCS.
Publish Date	2022-09-16 12:55
Citation	Jain M, Sable M, Tirpude AP, Sahu RN, Samanta SK, Das G. Histological difference in ligament flavum between degenerative lumbar canal stenosis and non-stenotic group: A prospective, comparative study. World J Orthop 2022; 13(9): 791-801
URL	https://www.wjgnet.com/2218-5836/full/v13/i9/791.htm
DOI	https://dx.doi.org/10.5312/wjo.v13.i9.791

Full Article (PDF)	WJO-13-791.pdf
Full Article (Word)	WJO-13-791.docx
Manuscript File	75180_Auto_Edited-LJH-LS.docx
Answering Reviewers	75180-Answering reviewers.pdf
Audio Core Tip	75180-Audio core tip.mp4
Biostatistics Review Certificate	75180-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	75180-Conflict-of-interest statement.pdf
Copyright License Agreement	75180-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	75180-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	75180-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	75180-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	75180-Language certificate.pdf
Peer-review Report	75180-Peer-review(s).pdf
Scientific Misconduct Check	75180-Bing-Liu JH-2.jpg
Scientific Misconduct Check	75180-CrossCheck.jpg
Scientific Editor Work List	75180-Scientific editor work list.pdf