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Articles Published Processes
7/4/2022 12:30:52 PM | Browse: 414 | Download: 867
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Received |
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2022-01-17 21:31 |
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Peer-Review Started |
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2022-01-17 21:32 |
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To Make the First Decision |
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Return for Revision |
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2022-03-08 05:43 |
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Revised |
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2022-03-20 20:07 |
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Second Decision |
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2022-05-13 02:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-05-14 07:37 |
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Articles in Press |
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2022-05-14 07:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-06-26 14:55 |
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Publish the Manuscript Online |
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2022-07-04 12:30 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Non-alcoholic fatty liver disease and the impact of genetic, epigenetic and environmental factors in the offspring
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Natalia Balassiano Wajsbrot, Nathalie Carvalho Leite, Gil F Salles and Cristiane A Villela-Nogueira |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Cristiane A Villela-Nogueira, FAASLD, MD, PhD, Full Professor, Department of Internal Medicine, Medical School, Federal University of Rio de Janeiro, Rua Professor Rodolpho Paulo Rocco, 255 Room 9E16, Rio de Janeiro 22750-240, Brazil. crisvillelanog@gmail.com |
| Key Words |
Steatosis; Genetic; Epigenetic; Environmental; Offspring; Non-alcoholic fatty liver disease |
| Core Tip |
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease and familial clustering has been described, although there is still some debate about this association. Among the factors that contribute to the disease in the offspring of NAFLD patients, genetic, epigenetic and environmental factors are the most plausible ones. In this review we describe the main genetic, environmental and epigenetic factors linked to NAFLD and the studies that investigate the relation of NAFLD in parents and its offspring. Although there are many experimental studies in animals, there is still much to be elucidated regarding studies and interventions in human beings. |
| Publish Date |
2022-07-04 12:30 |
| Citation |
Wajsbrot NB, Leite NC, Salles GF, Villela-Nogueira CA. Non-alcoholic fatty liver disease and the impact of genetic, epigenetic and environmental factors in the offspring. World J Gastroenterol 2022; 28(25): 2890-2899 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i25/2890.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i25.2890 |
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