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Articles Published Processes
7/27/2022 1:17:37 PM | Browse: 284 | Download: 449
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Received |
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2022-01-21 01:00 |
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Peer-Review Started |
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2022-01-21 01:01 |
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To Make the First Decision |
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Return for Revision |
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2022-06-07 06:58 |
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Revised |
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2022-06-20 14:24 |
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Second Decision |
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2022-07-04 03:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-07-06 04:40 |
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Articles in Press |
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2022-07-06 04:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-07-18 00:32 |
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Publish the Manuscript Online |
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2022-07-27 13:17 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Differential distribution of gene polymorphisms associated with hypercholesterolemia, hypertriglyceridemia, and hypoalphalipoproteinemia among Native American and Mestizo Mexicans
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rafael Torres-Valadez, Sonia Roman, Claudia Ojeda-Granados, Karina Gonzalez-Aldaco and Arturo Panduro |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Arturo Panduro, FAASLD, MD, PhD, Research Scientist, Department of Genomic Medicine in Hepatology, Civil Hospital of Guadalajara Fray Antonio Alcalde/Health Sciences Center, University of Guadalajara, Hospital # 278 Col. El Retiro, Guadalajara 44280, Jalisco, Mexico. apanduro@prodigy.net.mx |
| Key Words |
Dyslipidemia; Ethnicity; Genes; Obesity; Lipids; Liver disease; Diet |
| Core Tip |
Dyslipidemia is a metabolic alteration caused by gene-environmental interactions influenced by ethnicity. Genetic polymorphisms can modify the frequency and outcome of the hyperlipidemic state. Our results showed a differential distribution of gene polymorphisms associated with hypercholesterolemia (APOE4, LDLR), hypertriglyceridemia (APOE2, MTTP), and hypoalphalipoproteinemia (ABCA1) among Native Americans and Mestizo Mexicans of West Mexico. Hypercholesterolemia was the predominant dyslipidemia. In normal weight subjects, the APOB TT and LDLR GG genotypes increased the risk for hypercholesterolemia in the context of the Mestizo ethnicity. Regional personalized-medicine prevention strategies based on the host's genetic and environmental factors are required to decrease the prevalence of dyslipidemias. |
| Publish Date |
2022-07-27 13:17 |
| Citation |
Torres-Valadez R, Roman S, Ojeda-Granados C, Gonzalez-Aldaco K, Panduro A. Differential distribution of gene polymorphisms associated with hypercholesterolemia, hypertriglyceridemia, and hypoalphalipoproteinemia among Native American and Mestizo Mexicans. World J Hepatol 2022; 14(7): 1408-1420 |
| URL |
https://www.wjgnet.com/1948-5182/full/v14/i7/1408.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v14.i7.1408 |
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