ISSN |
2220-3206 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Psychiatry |
Manuscript Type |
Case Control Study |
Article Title |
ABCB9 polymorphism (rs61955196) is associated with schizophrenia in Chinese Han population
|
Manuscript Source |
Invited Manuscript |
All Author List |
Xin-Wei Li, Ming-Yuan Zhang, Zhi-Jun Li, Li-Zhe Ai, Meng-Di Jin, Ning-Ning Jia, Meng-Tong Xie, Yu-Qing Yang, Wei-Zhen Li, Lin Dong and Qiong Yu |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81673253 |
Jilin Provincial Ministry of Education S&T Project |
JJKH20190091KJ |
|
Corresponding Author |
Qiong Yu, MD, PhD, Professor, Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, No. 1163 Xinmin Street, Chaoyang District, Changchun 130021, Jilin Province, China. yuqiong@jlu.edu.cn |
Key Words |
Schizophrenia; Prenatal famine; rs61955196; DNA methylation; ABCB9 polymorphism |
Core Tip |
Prenatal famine exposure may cause changes in DNA methylation levels of genes, while maternal nutrition is a pivotal environmental factor for schizophrenia (SCZ). To analyze the association between prenatal famine exposure and SCZ risk, we recruited 443 SCZ patients and 511 healthy controls with four single-nucleotide polymorphisms genotyped, which were previously identified as DNA methylation quantitative trait locus. Our study observed significant differences in rs61955196 genotype distribution and allele frequency between SCZ patients and healthy controls for the first time, suggesting that rs61955196 in ABCB9 was associated with SCZ susceptibility among Northeast Han Chinese population. |
Publish Date |
2022-07-19 07:32 |
Citation |
Li XW, Zhang MY, Li ZJ, Ai LZ, Jin MD, Jia NN, Xie MT, Yang YQ, Li WZ, Dong L, Yu Q. ABCB9 polymorphism (rs61955196) is associated with schizophrenia in Chinese Han population. World J Psychiatry 2022; 12(7): 904-914 |
URL |
https://www.wjgnet.com/2220-3206/full/v12/i7/904.htm |
DOI |
https://dx.doi.org/10.5498/wjp.v12.i7.904 |