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Articles Published Processes
6/23/2022 2:39:01 PM | Browse: 423 | Download: 950
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Received |
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2022-01-26 10:23 |
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Peer-Review Started |
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2022-01-26 10:25 |
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To Make the First Decision |
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Return for Revision |
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2022-04-08 08:25 |
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Revised |
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2022-04-18 20:55 |
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Second Decision |
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2022-05-23 03:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-05-28 07:10 |
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Articles in Press |
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2022-05-28 07:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-05-19 23:37 |
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Typeset the Manuscript |
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2022-05-30 07:13 |
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Publish the Manuscript Online |
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2022-06-23 14:39 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Understanding fatigue in primary biliary cholangitis: From pathophysiology to treatment perspectives
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Erica Nicola Lynch, Claudia Campani, Tommaso Innocenti, Gabriele Dragoni, Maria Rosa Biagini, Paolo Forte and Andrea Galli |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Andrea Galli, MD, PhD, Professor, Gastroenterology Research Unit, Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence, Viale GB Morgagni 50, Florence 50134, Italy. andrea.galli@unifi.it |
| Key Words |
Fatigue; Primary biliary cholangitis; Treatment; Pathophysiology; Central fatigue; Peripheral fatigue |
| Core Tip |
Fatigue is considered one of the most frequent and debilitating symptoms in primary biliary cholangitis, affecting over 50% of patients. The objective of this review is to outline current understanding regarding the pathophysiology of fatigue, the role of comorbidities and contributing factors, the main tools for fatigue assessment, the failed therapeutic options, and future treatment perspectives for this disabling symptom. Since fatigue is an extremely common and debilitating symptom and there is still no licensed therapy for fatigue in PBC patients, further research is warranted to understand its causative mechanisms and to find effective treatment. |
| Publish Date |
2022-06-23 14:39 |
| Citation |
Lynch EN, Campani C, Innocenti T, Dragoni G, Biagini MR, Forte P, Galli A. Understanding fatigue in primary biliary cholangitis: From pathophysiology to treatment perspectives. World J Hepatol 2022; 14(6): 1111-1119 |
| URL |
https://www.wjgnet.com/1948-5182/full/v14/i6/1111.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v14.i6.1111 |
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