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5/26/2022 9:29:39 AM | Browse: 765 | Download: 2239
Publication Name World Journal of Stem Cells
Manuscript ID 75421
Country India
Received
2022-01-28 07:44
Peer-Review Started
2022-01-28 07:46
First Decision by Editorial Office Director
2022-03-11 23:43
Return for Revision
2022-03-11 23:43
Revised
2022-03-25 05:32
Publication Fee Transferred
Second Decision by Editor
2022-05-07 07:56
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2022-05-08 07:17
Articles in Press
2022-05-08 07:17
Edit the Manuscript by Language Editor
2022-04-28 20:53
Typeset the Manuscript
2022-05-23 07:36
Publish the Manuscript Online
2022-05-26 09:29
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Basic Study
Article Title Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection-a mechanistic study with integrating network biology
Manuscript Source Invited Manuscript
All Author List Dharmendra Kumar Maurya, Mayuri Bandekar and Santosh Kumar Sandur
ORCID
Author(s) ORCID Number
Dharmendra Kumar Maurya http://orcid.org/0000-0003-0909-363X
Mayuri Bandekar http://orcid.org/0000-0002-2176-9471
Santosh Kumar Sandur http://orcid.org/0000-0001-8852-4180
Funding Agency and Grant Number
Corresponding Author Dharmendra Kumar Maurya, BSc, MSc, PhD, N/A, N/A, Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, 3-82-S, A-block, Modular Laboratory, Mumbai 400085, Maharashtra, India. dkmaurya@barc.gov.in
Key Words Radioprotection; Mesenchymal stem cells; Wharton's jelly-derived mesenchymal stromal/stem cells; Cytokines; Granulocyte-colony stimulating factor; Network biology
Core Tip This study showed the potential role of cytokine granulocyte-colony stimulating factor in therapeutic radioprotection. Transcriptome analysis shows that Wharton's jelly-derived mesenchymal stromal/stem cells (WJ-MSCs) have unique set of genes compared to bone marrow MSCs and embryonic stem cells. WJ-MSCs secrete several cytokines which promote cellular pathways which handle tissue repair and regeneration.
Publish Date 2022-05-26 09:29
Citation Maurya DK, Bandekar M, Sandur SK. Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection: A mechanistic study with integrating network biology. World J Stem Cells 2022; 14(5): 347-361
URL https://www.wjgnet.com/1948-0210/full/v14/i5/347.htm
DOI https://dx.doi.org/10.4252/wjsc.v14.i5.347
Full Article (PDF) WJSC-14-347.pdf
Full Article (Word) WJSC-14-347.docx