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8/20/2014 9:00:00 PM | Browse: 985 | Download: 1106
Publication Name World Journal of Methodology
Manuscript ID 7561
Country/Territory Italy
Received
2013-11-25 14:37
Peer-Review Started
2013-11-25 21:30
To Make the First Decision
2013-12-25 18:11
Return for Revision
2013-12-26 20:23
Revised
2014-01-28 01:39
Second Decision
2014-04-17 14:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-04-17 15:08
Articles in Press
2014-05-23 12:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-05-14 08:31
Typeset the Manuscript
2014-07-08 20:35
Publish the Manuscript Online
2014-08-20 20:59
ISSN 2222-0682 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Hematology
Manuscript Type Review
Article Title Novel agents and new therapeutic approaches for treatment of multiple myeloma
Manuscript Source Invited Manuscript
All Author List Roberto Ria, Antonia Reale and Angelo Vacca
Funding Agency and Grant Number
Funding Agency Grant Number
Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research-AIRC)
Investigator Grant
5 per thousand Molecular Clinical Oncology Special Program 9965
European Commission's Seventh Framework programme (EU-FPT7) under grant agreement (OVER-MyR) 278706(to AV)
EU FPT7 (2007-2013) 278570(to DR)
MIUR PRIN 2009WCNS5C_004(to RR)
MIUR PRIN 2010NECHBX( to AV)
Corresponding Author Roberto Ria, MD, Section of Internal Medicine, Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Policlinico, Piazza Giulio Cesare 11, I-70124 Bari, Italy. roberto.ria@uniba.it
Key Words Immunomodulators; Multiple myeloma; New drugs; Proteasome inhibitors; Target therapy
Core Tip The aim of this review is to summarize and point out the current therapeutic strategies and the drugs actually in development for the management of multiple myeloma. The rationale of the new treatment strategies is found in their efficacy in targeting tumor cells and their microenvironment. Our understanding of multiple myeloma (MM) pathogenesis including the intracellular mechanisms as well as the interactions between MM cells and their microenvironment has helped the discovery of several targets that have become the focus of drug development. The goal is to improve patient’s survival and to control the disease in a long-term fashion, maintaining the quality of life of our patients.
Publish Date 2014-08-20 20:59
Citation Ria R, Reale A, Vacca A. Novel agents and new therapeutic approaches for treatment of multiple myeloma. World J Methodol 2014; 4(2): 73-90
URL http://www.wjgnet.com/2222-0682/full/v4/i2/73.htm
DOI http://dx.doi.org/10.5662/wjm.v4.i2.73
Full Article (PDF) WJM-4-73.pdf
Full Article (Word) WJM-4-73.doc
Manuscript File 7561-Review.doc
Answering Reviewers 7561-Answering Reviewers.pdf
Copyright License Agreement 7561-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 7561-Language certificate.pdf
Peer-review Report 7561-Peer review.pdf
Scientific Editor Work List 7561-Scientific editor work list.doc