Publication Name	World Journal of Cardiology
Manuscript ID	7584
Country	Italy

Received	2013-11-26 11:47
Peer-Review Started	2013-11-26 15:15
To Make the First Decision	2014-01-08 15:08
Return for Revision	2014-01-16 22:55
Revised	2014-01-22 23:36
Second Decision	2014-03-14 18:20
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-14 18:32
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-26 16:19
Typeset the Manuscript	2014-04-23 08:13
Publish the Manuscript Online	2014-04-24 19:19

ISSN	1949-8462 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Topic Highlights
Article Title	Clinical significance of glycated hemoglobin in the acute phase of ST elevation myocardial infarction
Manuscript Source	Invited Manuscript
All Author List	Chiara Lazzeri, Serafina Valente, Marco Chiostri, Maria Grazia D’Alfonso and Gian Franco Gensini
Funding Agency and Grant Number
Corresponding Author	Chiara Lazzeri, MD, Intensive Cardiac Care Unit, Heart and Vessel Department, Azienda Ospedaliero, Universitaria Careggi, Viale Morgagni 85, 50134 Florence, Italy. lazzeric@libero.it
Key Words	Glycated hemoglobin; ST-elevation myocardial infarction; Prognosis; Hyperglycemia; Glucose intolerance
Core Tip	Data on the prognostic role of glycated hemoglobin A1c (HbA1c) in patients with acute myocardial infarction (MI) are not univocal since they stem from studies which mainly differ in patients' selection criteria, therapy (thrombolysis vs mechanical revascularization) and number consistency. According to available evidence, in contemporary cohorts of ST-elevation myocardial infarction (STEMI) patients submitted to mechanical revascularization, HbA1c does not seem to be associated with short and long term mortality. However, in STEMI patients, HbA1c, even measured in the early phase, may represent a screening tool for glucose intolerance since its measurement can be performed in the non-fasting state and reflects average glucose concentration over the preceding 2-3 mo. We therefore proposed an algorithm based on pragmatic grounds which could be applied in STEMI patients without known diabetes in order to detect glucose intolerance abnormalities from the early phase. The main advantage of this algorithm is that it may help in tailoring the follow-up program, by helping in identifying patients at risk for the development of glucose intolerance after MI.
Publish Date	2014-04-24 19:19
Citation	Lazzeri C, Valente S, Chiostri M, D'Alfonso MG, Gensini GF. Clinical significance of glycated hemoglobin in the acute phase of ST elevation myocardial infarction. World J Cardiol 2014; 6(4): 140-147
URL	http://www.wjgnet.com/1949-8462/full/v6/i4/140.htm
DOI	http://dx.doi.org/10.4330/wjc.v6.i4.140

Full Article (PDF)	WJC-6-140.pdf
Full Article (Word)	WJC-6-140.doc
Manuscript File	7584-Review.doc
Answering Reviewers	7584-Answering reviewers.pdf
Copyright License Agreement	7584-Copyright assignment.pdf
Peer-review Report	7584-Peer review(s).pdf
Scientific Editor Work List	7584-Scientific editor work list.doc