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Articles Published Processes
8/10/2022 8:23:14 AM | Browse: 305 | Download: 616
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Received |
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2022-02-26 09:14 |
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Peer-Review Started |
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2022-02-26 09:17 |
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To Make the First Decision |
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Return for Revision |
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2022-05-09 22:28 |
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Revised |
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2022-06-03 16:13 |
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Second Decision |
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2022-07-18 03:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-07-22 03:17 |
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Articles in Press |
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2022-07-22 03:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-08-02 09:23 |
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Publish the Manuscript Online |
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2022-08-10 08:23 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Review |
| Article Title |
Role of one-step nucleic acid amplification in colorectal cancer lymph node metastases detection
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Francesco Crafa, Serafino Vanella, Onofrio A Catalano, Kelsey L Pomykala and Mario Baiamonte |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Francesco Crafa, MD, Director, Director, Division of General and Surgical Oncology, St. Giuseppe Moscati Hospital, Center of National Excellence and High Specialty, C/da Amoretta, Avellino 83100, Italy. crafa@tiscali.it |
| Key Words |
Colorectal malignancies; One-step nucleic acid amplification; Diagnostic accuracy; Negative predictive value; Upstaging; Organ-sparing surgery; Tailored lymphadenectomy |
| Core Tip |
Our findings suggest that the one-step nucleic acid amplification (OSNA) assay has high diagnostic accuracy and negative predictive value in detecting metastatic lymph nodes in colorectal cancer (CRC). The short turnaround time renders OSNA an attractive intra-operative method. OSNA results in upstaging in about 25% of stage II CRC cases. Moreover, organ-sparing surgery in early CRC and tailored lymphadenectomy, in more advanced cases, can be performed. |
| Publish Date |
2022-08-10 08:23 |
| Citation |
Crafa F, Vanella S, Catalano OA, Pomykala KL, Baiamonte M. Role of one-step nucleic acid amplification in colorectal cancer lymph node metastases detection. World J Gastroenterol 2022; 28(30): 4019-4043 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i30/4019.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i30.4019 |
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