| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Pre-sarcopenia and Mac-2 Binding Protein glycosylation isomer as predictors of re[NM1] currence and prognosis in early-stage hepatocellular carcinoma
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Masato Nakai, Kenichi Morikawa, Shunichi Hosoda, Sonoe Yoshida, Akinori Kubo, Yoshimasa Tokuchi, Takashi Kitagataya, Ren Yamada, Masatsugu Ohara, Takuya Sho, Goki Suda, Koji Ogawa and Naoya Sakamoto |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Kenichi Morikawa, MD, PhD, Professor, Department of Gastroenterology and Hepatology, Hokkaido University Faculty of Medicine and Graduate School of Medicine, Kita 15 Nishi 7, Kita-ku, Sapporo 060-8638, Japan. kenichi.morikawa@med.hokudai.ac.jp |
| Key Words |
Mac-2 binding protein; Mac-2 binding protein glycosylation isomer; Pre-sarcopenia; Primary hepatocellular carcinoma; Radiofrequency ablation |
| Core Tip |
Hepatocellular carcinoma (HCC) is prone to recurrence, even if cured at an early stage. Pre-sarcopenia has been reported to be a poor prognostic factor in the elderly population. The usefulness of the Mac-2 binding protein glycosylation isomer (M2BPGi) for the treatment of HCC has recently attracted attention. In this study, we investigated the recurrence and prognostic factors in patients who underwent radiofrequency ablation (RFA) for early-stage HCC. Based on our data, pre-sarcopenia and higher M2BPGi, but not M2BP[NM1] , were revealed as usefull predictors of tumor recurrence and poor prognosis for early-stage primary HCC in HCV-negative patients. |
| Publish Date |
2022-07-27 13:17 |
| Citation |
Nakai M, Morikawa K, Hosoda S, Yoshida S, Kubo A, Tokuchi Y, Kitagataya T, Yamada R, Ohara M, Sho T, Suda G, Ogawa K, Sakamoto N. Pre-sarcopenia and Mac-2 binding protein glycosylation isomer as predictors of recurrence and prognosis in early-stage hepatocellular carcinoma. World J Hepatol 2022; 14(7): 1480-1494 |
| URL |
https://www.wjgnet.com/1948-5182/full/v14/i7/1480.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v14.i7.1480 |
