Publication Name	World Journal of Methodology
Manuscript ID	76138
Country	India

Received	2022-03-05 05:43
Peer-Review Started	2022-03-05 05:45
To Make the First Decision
Return for Revision	2022-06-16 08:52
Revised	2022-06-29 09:57
Second Decision	2022-08-29 04:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-08-31 05:13
Articles in Press	2022-08-31 05:13
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-08-22 16:51
Typeset the Manuscript	2022-09-13 02:42
Publish the Manuscript Online	2022-09-16 10:39

ISSN	2222-0682 (online)
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Category	Biochemistry & Molecular Biology
Manuscript Type	Systematic Reviews
Article Title	Growth differentiation factor 15 as an emerging novel biomarker in SARS-CoV-2 infection
Manuscript Source	Invited Manuscript
All Author List	Deepak Parchwani, Sagar Dholariya, CDS Katoch and Ragini Singh
ORCID	Author(s) ORCID Number Deepak Parchwani http://orcid.org/0000-0001-5024-970X Sagar Dholariya http://orcid.org/0000-0002-0654-5998
Funding Agency and Grant Number
Corresponding Author	Sagar Dholariya, MD, Assistant Professor, Department of Biochemistry, All India Institute of Medical Sciences, Jamnagar Road, Khandheri, Rajkot 360001, Gujarat, India. drsagar.dholariya@gmail.com
Key Words	SARS-CoV-2; Growth differentiation factor 15; Biomarker; Risk-stratification; Prognosis
Core Tip	Growth differentiation factor (GDF)-15 levels are higher in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and higher levels are associated with disease severity, viremia and hypoxemia. The consistent increase in the concentration of GDF-15 during a hospital stay is associated with worse outcomes. Hence, serial monitoring of GDF-15 concentrations may provide useful prognostic value for hospitalized patients with SARS-CoV-2. GDF-15 appears to be involved in the underlying pathophysiology, laying the foundation for a novel therapeutic approach for SARS-CoV-2.
Publish Date	2022-09-16 10:39
Citation	Parchwani D, Dholariya S, Katoch C, Singh R. Growth differentiation factor 15 as an emerging novel biomarker in SARS-CoV-2 infection. World J Methodol 2022; 12(5): 438-447
URL	https://www.wjgnet.com/2222-0682/full/v12/i5/438.htm
DOI	https://dx.doi.org/10.5662/wjm.v12.i5.438

Full Article (PDF)	WJM-12-438.pdf
Full Article (Word)	WJM-12-438.docx
Manuscript File	76138_Auto_Edited-LM.docx
Answering Reviewers	76138-Answering reviewers.pdf
Audio Core Tip	76138-Audio core tip.aac
Biostatistics Review Certificate	76138-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	76138-Conflict-of-interest statement.pdf
Copyright License Agreement	76138-Copyright license agreement.pdf
Peer-review Report	76138-Peer-review(s).pdf
Scientific Misconduct Check	76138-Bing-Liu JH-2.jpg
Scientific Misconduct Check	76138-CrossCheck.jpg
Scientific Editor Work List	76138-Scientific editor work list.pdf
CrossCheck Report	76138-CrossCheck report.pdf