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Articles Published Processes
9/9/2022 12:48:14 PM | Browse: 444 | Download: 1195
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Received |
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2022-03-16 00:22 |
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Peer-Review Started |
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2022-03-16 00:24 |
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To Make the First Decision |
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Return for Revision |
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2022-04-17 03:22 |
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Revised |
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2022-05-05 16:06 |
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Second Decision |
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2022-07-21 03:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-07-26 19:06 |
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Articles in Press |
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2022-07-26 19:06 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-08-26 01:30 |
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Publish the Manuscript Online |
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2022-09-09 12:48 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alya R Alnuaimi, Vidhya A Nair, Lara J Bou Malhab, Eman Abu-Gharbieh, Anu Vinod Ranade, Gianfranco Pintus, Mohamad Hamad, Hauke Busch, Jutta Kirfel, Rifat Hamoudi and Wael M Abdel-Rahman |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wael M Abdel-Rahman, MD, PhD, Professor, Department of Medical Laboratory Sciences, University of Sharjah, University City, Sharjah 27272, United Arab Emirates. whassan@sharjah.ac.ae |
| Key Words |
Bladder cancer; CALD1; Caldesmon; Chemoresistance; Colorectal cancer; Gastric cancer; Glioma; Epithelial to mesenchymal transition; Invasion; Metastasis |
| Core Tip |
The actin-binding protein caldesmon (CaD) plays an important role in cancer development, metastasis, and resistance to chemotherapy. CaD has emerged as a significant player in carcinogenesis, as it features many cancer hallmarks, including epithelial mesenchymal transition, angiogenesis, and immune evasion. Interestingly, CaD undergoes selective tumor-specific splicing, and the resulting isoforms are generally not expressed in normal tissues. These data qualify CaD as an attractive candidate for targeted therapy in addition to its role in the diagnosis and prognosis of cancer. |
| Publish Date |
2022-09-09 12:48 |
| Citation |
Alnuaimi AR, Nair VA, Malhab LJB, Abu-Gharbieh E, Ranade AV, Pintus G, Hamad M, Busch H, Kirfel J, Hamoudi R, Abdel-Rahman WM. Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers. World J Gastrointest Oncol 2022; 14(9): 1637-1653 |
| URL |
https://www.wjgnet.com/1948-5204/full/v14/i9/1637.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v14.i9.1637 |
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