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Articles Published Processes
9/2/2022 6:17:49 AM | Browse: 479 | Download: 1524
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Received |
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2022-03-16 22:23 |
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Peer-Review Started |
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2022-03-16 22:39 |
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To Make the First Decision |
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Return for Revision |
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2022-04-10 07:01 |
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Revised |
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2022-04-21 08:17 |
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Second Decision |
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2022-08-11 03:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-08-16 21:41 |
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Articles in Press |
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2022-08-16 21:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-06-16 00:29 |
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Typeset the Manuscript |
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2022-08-22 10:10 |
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Publish the Manuscript Online |
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2022-09-02 06:17 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Local inflammatory response to gastroesophageal reflux: Association of gene expression of inflammatory cytokines with esophageal multichannel intraluminal impedance-pH data
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sergey Morozov and Tatyana Sentsova |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministry of Science and Higher Education of Russia |
FGMF-2022-0005 |
| Ministry of Science and Higher Education of Russia |
0410-2020-0007 |
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| Corresponding Author |
Sergey Morozov, MD, PhD, Doctor, Doctor, Senior Researcher, Department of Gastroenterology, Hepatology and Nutrition, Federal Research Center of Nutrition, Biotechnology and Food Safety, Kashirskoye shosse, 21, Moscow 115446, Russia. morosoffsv@mail.ru |
| Key Words |
Gastroesophageal reflux disease; Gene expression; Cytokines; Erosive esophagitis; Non-erosive gastroesophageal reflux disease; Esophageal multichannel intraluminal impedance-pH; Gastroesophageal reflux |
| Core Tip |
Local expression of cytokines may be involved in pathophysiology of different forms of gastroesophageal reflux disease. We found a different profile of local expression of cytokines in subgroups of patients with erosive esophagitis and non-erosive forms of gastroesophageal reflux disease. For the first time we have revealed a correlation between gene expression of interleukin-18, tumor necrosis factor alpha, GATA binding protein 3, toll-like receptor 4, differentiation cluster 68 and mean esophageal pH and an association of acid exposure with expression of interleukin-1β, interleukin-18, tumor necrosis factor alpha, toll-like receptor 4, differentiation cluster 68 and β-2 microglobulin. |
| Publish Date |
2022-09-02 06:17 |
| Citation |
Morozov S, Sentsova T. Local inflammatory response to gastroesophageal reflux: Association of gene expression of inflammatory cytokines with esophageal multichannel intraluminal impedance-pH data. World J Clin Cases 2022; 10(26): 9254-9263 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i26/9254.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i26.9254 |
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