Publication Name	World Journal of Gastroenterology
Manuscript ID	7644
Country	Ireland

Received	2013-11-27 16:18
Peer-Review Started	2013-11-28 09:13
To Make the First Decision	2014-02-26 15:20
Return for Revision	2014-03-13 18:34
Revised	2014-03-19 00:39
Second Decision	2014-05-14 09:18
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-14 09:37
Articles in Press	2014-05-23 09:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-10 09:04
Publish the Manuscript Online	2014-07-21 17:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Microbiota-host interactions in irritable bowel syndrome: Epithelial barrier, immune regulation and brain-gut interactions
Manuscript Source	Invited Manuscript
All Author List	Niall P Hyland, Eamonn MM Quigley and Elizabeth Brint
Funding Agency and Grant Number
Corresponding Author	Elizabeth Brint, PhD, Department of Pathology, University College Cork, Coláiste Na Hollscoile, Bóthar an Choláiste, Co. Corcaigh, 30 Cork, Ireland. e.brint@ucc.ie
Key Words	Microbiota; Irritable bowel syndrome; Toll-like receptor; Epithelial barrier; Gut-brain axis
Core Tip	Recent discoveries have kindled an interest in microbiota-host interactions in irritable bowel syndrome (IBS) and have led to new lines of research into this common and elusive disorder. It is clear that the microbiota is altered in IBS and that such alterations could well contribute to the pathogenesis of the disorder through, for example, increased permeability, an altered immune profile, effects on the central nervous system and modulation of gut neuromuscular function. This review will explore these host-microbe interactions and their relevance to the pathogenesis of IBS. This review will explore these interactions and their relevance to the pathogenesis of IBS.
Publish Date	2014-07-21 17:17
Citation	Hyland NP, Quigley EMM, Brint E. Microbiota-host interactions in irritable bowel syndrome: Epithelial barrier, immune regulation and brain-gut interactions. World J Gastroenterol 2014; 20(27): 8859-8866
URL	http://www.wjgnet.com/1007-9327/full/v20/i27/8859.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i27.8859

Full Article (PDF)	WJG-20-8859.pdf
Full Article (Word)	WJG-20-8859.doc
Manuscript File	7644-Review.docx
Answering Reviewers	7644-Answering reviewers.pdf
Copyright License Agreement	7644-Copyright assignment.pdf
Peer-review Report	7644-Peer reviews.pdf
Scientific Editor Work List	7644-Scientific editor work list.pdf