Publication Name	World Journal of Stem Cells
Manuscript ID	76480
Country	China

Received	2022-03-19 14:48
Peer-Review Started	2022-03-19 14:50
To Make the First Decision
Return for Revision	2022-04-18 23:01
Revised	2022-05-15 19:22
Second Decision	2022-07-06 08:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-07-11 18:56
Articles in Press	2022-07-11 18:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-07-20 00:52
Publish the Manuscript Online	2022-07-26 11:15

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Review
Article Title	Application of exosome-derived noncoding RNAs in bone regeneration: Opportunities and challenges
Manuscript Source	Invited Manuscript
All Author List	Yuan-Zhong Ren, Shan-Shan Ding, Ya-Ping Jiang, Hui Wen and Tao Li
ORCID	Author(s) ORCID Number Yuan-Zhong Ren http://orcid.org/0000-0003-0020-4006 Shan-Shan Ding http://orcid.org/0000-0003-4870-283X Ya-Ping Jiang http://orcid.org/0000-0002-6614-0079 Hui Wen http://orcid.org/0000-0003-0306-1557 Tao Li http://orcid.org/0000-0002-0698-2960
Funding Agency and Grant Number	Funding Agency Grant Number Qingdao Traditional Chinese Medicine Science and Technology Project 2021-zyym28 Science and technology Development Project of Shandong Geriatric Society LKJGG2021W082
Corresponding Author	Tao Li, MD, Postdoc, Surgeon, Department of Joint Surgery, The Affiliated Hospital of Qingdao University, No. 59 Haier Road, Qingdao 266003, Shandong Province, China. qdult@qdu.edu.cn
Key Words	Exosomes; Non-coding RNA; Bone; Osteogenesis; Angiogenesis; Osteoclasts
Core Tip	The key to bone regeneration is the mutual balance between osteoblasts, osteoclasts and angiogenesis. As a critical factor in bone regeneration, exosome-derived noncoding RNA (exo-ncRNA) has been extensively studied. However, the detailed mechanism of exo-ncRNA in bone regeneration is still unclear, and further research is necessary. This article summarizes the research on exo-ncRNA in bone regeneration.
Publish Date	2022-07-26 11:15
Citation	Ren YZ, Ding SS, Jiang YP, Wen H, Li T. Application of exosome-derived noncoding RNAs in bone regeneration: Opportunities and challenges. World J Stem Cells 2022; 14(7): 473-489
URL	https://www.wjgnet.com/1948-0210/full/v14/i7/473.htm
DOI	https://dx.doi.org/10.4252/wjsc.v14.i7.473

Full Article (PDF)	WJSC-14-473.pdf
Full Article (Word)	WJSC-14-473.docx
Manuscript File	76480_Auto_Edited-LS.docx
Answering Reviewers	76480-Answering reviewers.pdf
Audio Core Tip	76480-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	76480-Conflict-of-interest statement.pdf
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Non-Native Speakers of English Editing Certificate	76480-Language certificate.pdf
Supplementary Material	76480-Copyright permission.pdf
Peer-review Report	76480-Peer-review(s).pdf
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Scientific Editor Work List	76480-Scientific editor work list.pdf