Publication Name	World Journal of Diabetes
Manuscript ID	76609
Country	India

Received	2022-03-22 14:36
Peer-Review Started	2022-03-22 14:37
To Make the First Decision
Return for Revision	2022-05-11 21:31
Revised	2022-05-17 06:46
Second Decision	2022-07-22 07:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-07-25 03:21
Articles in Press	2022-07-25 03:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-08-07 14:16
Publish the Manuscript Online	2022-08-12 11:48

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Critical Care Medicine
Manuscript Type	Systematic Reviews
Article Title	Metformin toxicity: A meta-summary of case reports
Manuscript Source	Invited Manuscript
All Author List	Deven Juneja, Prashant Nasa and Ravi Jain
ORCID	Author(s) ORCID Number Deven Juneja http://orcid.org/0000-0002-8841-5678 Prashant Nasa http://orcid.org/0000-0003-1948-4060 Ravi Jain http://orcid.org/0000-0001-9260-479X
Funding Agency and Grant Number
Corresponding Author	Deven Juneja, Visiting Professor, FCCP, MBBS, Director, Director, Institute of Critical Care Medicine, Max Super Speciality Hospital, Saket, 1 Press Enclave Road, New Delhi 110017, India. devenjuneja@gmail.com
Key Words	Extracorporeal toxin removal; Haemodialysis; Metformin associated lactic acidosis; Metformin overdose; Renal replacement therapy
Core Tip	Metformin may be associated with significant toxicity, even when used in therapeutic doses, of which metformin associated lactic acidosis is the most commonly reported toxicity. These patients may have favourable outcomes in spite of consumption of high doses, severe acidosis, and high serum lactate and metformin concentrations. Early aggressive supportive care, use of renal replacement therapy for toxin removal and organ support may help in improving outcomes.
Publish Date	2022-08-12 11:48
Citation	Juneja D, Nasa P, Jain R. Metformin toxicity: A meta-summary of case reports. World J Diabetes 2022; 13(8): 654-664
URL	https://www.wjgnet.com/1948-9358/full/v13/i8/654.htm
DOI	https://dx.doi.org/10.4239/wjd.v13.i8.654

Full Article (PDF)	WJD-13-654.pdf
Full Article (Word)	WJD-13-654.docx
PRISMA 2009 Checklist	76609-PRISMA-2009-Checklist-revision.doc
Manuscript File	76609_Auto_Edited-LS.docx
Answering Reviewers	76609-Answering reviewers.pdf
Audio Core Tip	76609-Audio core tip.m4a
Biostatistics Review Certificate	76609-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	76609-Conflict-of-interest statement.pdf
Copyright License Agreement	76609-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	76609-Language certificate.pdf
Supplementary Material	76609-Supplementary material.pdf
Peer-review Report	76609-Peer-review(s).pdf
Scientific Misconduct Check	76609-Bing-Fan JR-2.png
Scientific Editor Work List	76609-Scientific editor work list.pdf
CrossCheck Report	76609-CrossCheck report.pdf
CrossCheck Report	76609-CrossCheck.png