| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Retrospective Study |
| Article Title |
Comparison of demographic features and laboratory parameters between COVID-19 deceased patients and surviving severe and critically ill cases
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lei Wang, Yang Gao, Zhao-Jin Zhang, Chang-Kun Pan, Ying Wang, Yu-Cheng Zhu, Yan-Peng Qi, Feng-Jie Xie, Xue Du, Na-Na Li, Peng-Fei Chen, Chuang-Shi Yue, Ji-Han Wu, Xin-Tong Wang, Yu-Jia Tang, Qi-Qi Lai and Kai Kang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81902000 |
|
| Corresponding Author |
Kai Kang, MMed, Chief Doctor, Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, No. 23 Post Street, Harbin 150001, Heilongjiang Province, China. janekk79@126.com |
| Key Words |
COVID-19; SARS-CoV-2; Deceased patients; C-reactive protein; D-dimer; Neutrophil percentage; Lymphocyte count; Platelet |
| Core Tip |
Early detection and intervention of coronavirus disease 2019 (COVID-19) patients with a higher risk of death will contribute to rationally allocate limited medical resources and reduce the case-fatality rate. Our results illustrated that some laboratory parameters, including neutrophil percentage (NEUT%), platelet (PLT), C-reactive protein (CRP), creatine kinase isoenzyme, serum troponin I and brain natriuretic peptides showed significant differences in COVID-19 deceased patients compared with surviving severe and critically ill cases. COVID-19 deceased patients had higher CRP, D-dimer and NEUT% levels and lower lymphocyte count and PLT counts. Our study added evidence to the notion that the pathogenesis of COVID-19 deceased patients was related to the superimposed bacterial or fungal infection, cellular immune deficiency, coagulation disorder, activation of inflammatory cytokine responses, and impaired organ function, which in turn could interact with each other, forming a complicated network. |
| Publish Date |
2022-08-01 09:20 |
| Citation |
Wang L, Gao Y, Zhang ZJ, Pan CK, Wang Y, Zhu YC, Qi YP, Xie FJ, Du X, Li NN, Chen PF, Yue CS, Wu JH, Wang XT, Tang YJ, Lai QQ, Kang K. Comparison of demographic features and laboratory parameters between COVID-19 deceased patients and surviving severe and critically ill cases. World J Clin Cases 2022; 10(23): 8161-8169 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i23/8161.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i23.8161 |
