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Articles Published Processes
7/11/2022 8:36:00 AM | Browse: 195 | Download: 407
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Received |
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2022-03-25 02:55 |
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Peer-Review Started |
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2022-03-25 02:57 |
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To Make the First Decision |
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Return for Revision |
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2022-04-13 10:39 |
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Revised |
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2022-04-17 23:19 |
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Second Decision |
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2022-05-30 02:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-06-03 21:09 |
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Articles in Press |
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2022-06-03 21:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-07-02 10:45 |
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Publish the Manuscript Online |
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2022-07-11 08:36 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Clinical and Translational Research |
Article Title |
Expression of hepatocyte nuclear factor 4 alpha, wingless-related integration site, and β-catenin in clinical gastric cancer
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Qian Hu, Ling-Li Li, Ze Peng and Ping Yi |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China (General Program) |
81673757 |
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Corresponding Author |
Ping Yi, MD, PhD, Doctor, Department of Integrated Traditional Chinese and Western Medicine, Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jie Fang Avenue, Wuhan 430030, Hubei Province, China. pyi219@163.com |
Key Words |
B-catenin; Biomarker; Gastric cancer; Hepatocyte nuclear factor 4 alpha; Wingless-related integration site |
Core Tip |
Gastric cancer (GC) is the second most common cause of cancer-related deaths worldwide. A precise biopsy biomarker that can predict the progression of GC and change its prognosis is urgently needed. We previously found that hepatocyte nuclear factor 4 alpha (HNF4α)/wingless-related integration site (WNT) signaling is involved in the process of GC in preclinical models. Here, we obtained gastric tumor and para-cancerous tissue sections from Tongji Hospital and investigated the expression of HNF4α, WNT5a, and β-catenin. The expression of HNF4α and WNT5a could serve as an early diagnostic biomarker of GC. |
Publish Date |
2022-07-11 08:36 |
Citation |
Hu Q, Li LL, Peng Z, Yi P. Expression of hepatocyte nuclear factor 4 alpha, wingless-related integration site, and β-catenin in clinical gastric cancer. World J Clin Cases 2022; 10(21): 7242-7255 |
URL |
https://www.wjgnet.com/2307-8960/full/v10/i21/7242.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v10.i21.7242 |
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