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7/11/2022 8:36:00 AM | Browse: 195 | Download: 407
Publication Name World Journal of Clinical Cases
Manuscript ID 76672
Country China
Received
2022-03-25 02:55
Peer-Review Started
2022-03-25 02:57
To Make the First Decision
Return for Revision
2022-04-13 10:39
Revised
2022-04-17 23:19
Second Decision
2022-05-30 02:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-06-03 21:09
Articles in Press
2022-06-03 21:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-07-02 10:45
Publish the Manuscript Online
2022-07-11 08:36
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Clinical and Translational Research
Article Title Expression of hepatocyte nuclear factor 4 alpha, wingless-related integration site, and β-catenin in clinical gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Qian Hu, Ling-Li Li, Ze Peng and Ping Yi
ORCID
Author(s) ORCID Number
Qian Hu http://orcid.org/0000-0002-5783-7085
Ling-Li Li http://orcid.org/0000-0003-4518-1418
Ze Peng http://orcid.org/0000-0003-2175-4322
Ping Yi http://orcid.org/0000-0001-8560-2024
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China (General Program) 81673757
Corresponding Author Ping Yi, MD, PhD, Doctor, Department of Integrated Traditional Chinese and Western Medicine, Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jie Fang Avenue, Wuhan 430030, Hubei Province, China. pyi219@163.com
Key Words B-catenin; Biomarker; Gastric cancer; Hepatocyte nuclear factor 4 alpha; Wingless-related integration site
Core Tip Gastric cancer (GC) is the second most common cause of cancer-related deaths worldwide. A precise biopsy biomarker that can predict the progression of GC and change its prognosis is urgently needed. We previously found that hepatocyte nuclear factor 4 alpha (HNF4α)/wingless-related integration site (WNT) signaling is involved in the process of GC in preclinical models. Here, we obtained gastric tumor and para-cancerous tissue sections from Tongji Hospital and investigated the expression of HNF4α, WNT5a, and β-catenin. The expression of HNF4α and WNT5a could serve as an early diagnostic biomarker of GC.
Publish Date 2022-07-11 08:36
Citation Hu Q, Li LL, Peng Z, Yi P. Expression of hepatocyte nuclear factor 4 alpha, wingless-related integration site, and β-catenin in clinical gastric cancer. World J Clin Cases 2022; 10(21): 7242-7255
URL https://www.wjgnet.com/2307-8960/full/v10/i21/7242.htm
DOI https://dx.doi.org/10.12998/wjcc.v10.i21.7242
Full Article (PDF) WJCC-10-7242.pdf
Full Article (Word) WJCC-10-7242.docx
Manuscript File 76672_Auto_Edited-YJM-LS.docx
Answering Reviewers 76672-Answering reviewers.pdf
Audio Core Tip 76672-Audio core tip.m4a
Biostatistics Review Certificate 76672-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 76672-Conflict-of-interest statement.pdf
Copyright License Agreement 76672-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 76672-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 76672-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 76672-Language certificate.pdf
Supplementary Material 76672-Supplementary material.pdf
Peer-review Report 76672-Peer-review(s).pdf
Scientific Editor Work List 76672-Scientific editor work list.pdf