Publication Name	World Journal of Hepatology
Manuscript ID	76739
Country	Russia

Received	2022-03-29 11:34
Peer-Review Started	2022-03-29 11:37
To Make the First Decision
Return for Revision	2022-05-12 08:28
Revised	2022-05-25 06:51
Second Decision	2022-06-27 03:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-06-27 17:03
Articles in Press	2022-06-27 17:03
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-06-22 01:39
Typeset the Manuscript	2022-07-01 01:47
Publish the Manuscript Online	2022-07-27 13:17

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Hepatitis B virus markers in hepatitis B surface antigen negative patients with pancreatic cancer: Two case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Sergey Batskikh, Sergey Morozov and Dmitry Kostyushev
ORCID	Author(s) ORCID Number Sergey Batskikh http://orcid.org/0000-0002-5917-203X Sergey Morozov http://orcid.org/0000-0001-6816-3058 Dmitry Kostyushev http://orcid.org/0000-0002-1851-7441
Funding Agency and Grant Number	Funding Agency Grant Number Moscow Department of Health AAAA-A18-118021590196-1 Ministry of Science and Higher Education FGMF-2022-0005 Russian Science Foundation 20-15-00373
Corresponding Author	Sergey Morozov, MD, PhD, Doctor, Senior Researcher, Department of Gastroenterology, Hepatology and Nutrition, Federal Research Center of Nutrition and Biotechnology, Kashirskoye Shosse 21, Moscow 115446, Russia. morosoffsv@mail.ru
Key Words	Pancreatic cancer; Pancreatic ductal adenocarcinoma; Hepatitis B virus; Previous hepatitis B; Anti-HBc; Hepatitis B virus X antigen
Core Tip	Hepatitis B virus (HBV) is a known carcinogen that may be involved in pancreatic cancer (PC) development. Detection of HBV biomarkers (especially - expression of HBx) within the tumor tissue may provide direct support for this. However, there is still a lack of such reports, particularly in non-endemic for HBV infection regions. In the report of case series, we present two cases of HBsAg-negative patients with pancreatic ductal adenocarcinoma, in whom the markers of HBV were detected in blood and in the tumor tissue. This reflects potential participation of the virus in the etiology and pathogenesis of pancreatic ductal adenocarcinoma.
Publish Date	2022-07-27 13:17
Citation	Batskikh S, Morozov S, Kostyushev D. Hepatitis B virus markers in hepatitis B surface antigen negative patients with pancreatic cancer: Two case reports. World J Hepatol 2022; 14(7): 1512-1519
URL	https://www.wjgnet.com/1948-5182/full/v14/i7/1512.htm
DOI	https://dx.doi.org/10.4254/wjh.v14.i7.1512

Full Article (PDF)	WJH-14-1512.pdf
Full Article (Word)	WJH-14-1512.docx
CARE Checklist–2016	76739-CARE-Checklist–2016-revision.pdf
Manuscript File	76739_Auto_Edited-LM.docx
Answering Reviewers	76739-Answering reviewers.pdf
Audio Core Tip	76739-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	76739-Conflict-of-interest statement.pdf
Copyright License Agreement	76739-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	76739-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s)	76739-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	76739-Language certificate.pdf
Supplementary Material	76739-Supplementary material.pdf
Peer-review Report	76739-Peer-review(s).pdf
Scientific Misconduct Check	76739-Bing-Wang LL-2.png
Scientific Editor Work List	76739-Scientific editor work list.pdf