Publication Name	World Journal of Hepatology
Manuscript ID	7687
Country	Italy

Received	2013-11-28 14:59
Peer-Review Started	2013-11-29 14:08
First Decision by Editorial Office Director
Return for Revision	2014-03-04 20:41
Revised	2014-03-16 22:44
Publication Fee Transferred
Second Decision by Editor	2014-06-03 16:13
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-06-03 16:27
Articles in Press	2014-06-03 16:47
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-25 09:00
Publish the Manuscript Online	2014-07-04 18:01

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Clinical impact of occult hepatitis B virus infection in immunosuppressed patients
Manuscript Source	Invited Manuscript
All Author List	Evangelista Sagnelli, Mariantonietta Pisaturo, Salvatore Martini, Pietro Filippini, Caterina Sagnelli and Nicola Coppola
Funding Agency and Grant Number
Corresponding Author	Evangelista Sagnelli, Professor, Department of Public Medicine, Section of Infectious Diseases, Second University of Naples, Via: L. Armanni 5, 80131 Naples, Italy. evangelista.sagnelli@yahoo.it
Key Words	Occult hepatitis B virus infection; Silent hepatitis B virus infection; Hepatitis C virus infection; Liver fibrosis
Core Tip	In occult Hepatitis B infection (OBI), hepatitis B virus reactivation is more common in anti-HIV-positive subjects, in those in onco-hematological settings, in patients who undergo hemopoietic stem cell transplantation and in those treated with anti-CD20 or anti-CD52 monoclonal antibody. Reactivation may be severe and in nearly 20% of cases it may take a life-threatening course. The use of nucleot(s)ide analogues to prevent this reactivation is mandatory in HBsAg-negative/anti-HBc-positive patients in all conditions of strong and/or prolonged immunosuppression. We describe the characteristics of OBI in onco-hematological and rheumatological diseases, in solid cancers and in HIV infection.
Publish Date	2014-07-04 18:01
Citation	Sagnelli E, Pisaturo M, Martini S, Filippini P, Sagnelli C, Coppola N. Clinical impact of occult hepatitis B virus infection in immunosuppressed patients. World J Hepatol 2014; 6(6): 384-393
URL	http://www.wjgnet.com/1948-5182/full/v6/i6/384.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i6.384

Full Article (PDF)	WJH-6-384.pdf
Full Article (Word)	WJH-6-384.doc
Manuscript File	7687-Review.docx
Answering Reviewers	7687-Answering reviewers.pdf
Copyright License Agreement	7687-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7687-Language certificate.pdf
Peer-review Report	7687-Peer review(s).pdf
Scientific Misconduct Check	7687-CrossCheck.jpg
Scientific Editor Work List	7687-Scientific editor work list.pdf