Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	76974
Country	United States

Received	2022-04-13 14:07
Peer-Review Started	2022-04-13 14:10
To Make the First Decision
Return for Revision	2022-06-16 10:33
Revised	2022-06-22 03:22
Second Decision	2022-07-25 07:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-07-31 20:39
Articles in Press	2022-07-31 20:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-08-29 08:16
Publish the Manuscript Online	2022-08-31 08:14

ISSN	2150-5349 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Impact of epinephrine volume on further bleeding due to high-risk peptic ulcer disease in the combination therapy era
Manuscript Source	Unsolicited Manuscript
All Author List	Saad Saffo and Anil Nagar
ORCID	Author(s) ORCID Number Saad Saffo http://orcid.org/0000-0001-5375-3100 Anil Nagar http://orcid.org/0000-0003-4946-209X
Funding Agency and Grant Number	Funding Agency Grant Number National Institutes of Health T32 2T32DK007356-42
Corresponding Author	Saad Saffo, MD, Academic Fellow, Section of Digestive Diseases, Yale University School of Medicine, 333 Cedar Street, 1080 LMP, New Haven, CT 06520, United States. saad.saffo@yale.edu
Key Words	Peptic ulcer disease; Gastrointestinal bleeding; Upper endoscopy; Endoscopic hemostasis; Epinephrine
Core Tip	To our knowledge, this is the only study specifically aimed at clarifying the impact of epinephrine volume in patients treated with combination endoscopic therapy. Our findings suggest that larger volumes of epinephrine are unlikely to improve clinical outcomes among patients who also receive thermal therapy and/or clipping.
Publish Date	2022-08-31 08:14
Citation	Saffo S, Nagar A. Impact of epinephrine volume on further bleeding due to high-risk peptic ulcer disease in the combination therapy era. World J Gastrointest Pharmacol Ther 2022; 10(5): 67-76
URL	https://www.wjgnet.com/2150-5349/full/v13/i5/67.htm
DOI	https://dx.doi.org/10.4292/wjgpt.v13.i5.67

Full Article (PDF)	WJGPT-13-67.pdf
Full Article (Word)	WJGPT-13-67.docx
STROBE Statement	76974-STROBE-Statement-revision.docx
Manuscript File	76974_Auto_Edited-LS.docx
Answering Reviewers	76974-Answering reviewers.pdf
Audio Core Tip	76974-Audio core tip.mp3
Biostatistics Review Certificate	76974-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	76974-Conflict-of-interest statement.pdf
Copyright License Agreement	76974-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	76974-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	76974-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	76974-Institutional review board statement.pdf
Peer-review Report	76974-Peer-review(s).pdf
Scientific Misconduct Check	76974-Bing-Wang LL-2.png
Scientific Editor Work List	76974-Scientific editor work list.pdf
CrossCheck Report	76974-CrossCheck report.pdf