Publication Name	World Journal of Hepatology
Manuscript ID	7710
Country	United States

Received	2013-11-28 18:28
Peer-Review Started	2013-11-29 23:10
First Decision by Editorial Office Director
Return for Revision	2014-02-19 21:31
Revised	2014-02-23 23:53
Publication Fee Transferred
Second Decision by Editor	2014-06-03 16:19
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-06-03 16:33
Articles in Press	2014-06-03 16:49
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-22 17:22
Publish the Manuscript Online	2014-07-25 16:43

ISSN	1948-5182 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Colorectal hepatic metastasis: Evolving therapies
Manuscript Source	Invited Manuscript
All Author List	Francisco Igor B Macedo and Tafadzwa Makarawo
Funding Agency and Grant Number
Corresponding Author	Francisco Igor B Macedo, MD, Department of Surgery, Providence Hospital and Medical Centers, 16001 W Nine Mile Rd, Southfield, MI 48075, United States. franciscoigor.macedo@stjohn.org
Key Words	Colorectal cancer; Hepatic metastasis; Hepatectomy; Survival; Chemotherapy; 5-fluorouracil leucovorin and oxaliplatin
Core Tip	The management of colorectal hepatic metastasis is complex, and should involve a multidisciplinary tumor board involving specialized medical and surgical oncologists. Although liver resection still remains as the key step in the management of liver metastasis, the introduction of new chemotherapeutic regimens and recent adjunct therapies, including radiofrequency ablation, cryotherapy and radioembolization improved patient care, and prolonged survival in patients with unresectable disease.
Publish Date	2014-07-25 16:43
Citation	Macedo FI, Makarawo T. Colorectal hepatic metastasis: Evolving therapies. World J Hepatol 2014; 6(7): 453-463
URL	http://www.wjgnet.com/1948-5182/full/v6/i7/453.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i7.453

Full Article (PDF)	WJH-6-453.pdf
Full Article (Word)	WJH-6-453.doc
Manuscript File	7710-Review.doc
Answering Reviewers	7710-Answering reviewers.pdf
Copyright License Agreement	7710-Copyright assignment.pdf
Peer-review Report	7710-Peer review(s).pdf
Scientific Misconduct Check	7710-CrossCheck.jpg
Scientific Editor Work List	7710-Scientific editor work list.pdf