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Articles Published Processes
9/27/2022 1:00:17 PM | Browse: 347 | Download: 909
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Received |
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2022-04-17 10:43 |
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Peer-Review Started |
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2022-04-17 10:45 |
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To Make the First Decision |
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Return for Revision |
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2022-05-13 01:44 |
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Revised |
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2022-05-23 03:20 |
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Second Decision |
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2022-08-24 02:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-08-25 17:49 |
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Articles in Press |
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2022-08-25 17:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-08-22 17:04 |
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Typeset the Manuscript |
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2022-09-07 07:43 |
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Publish the Manuscript Online |
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2022-09-27 13:00 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Minireviews |
| Article Title |
Review of the pharmacological effects of astragaloside IV and its autophagic mechanism in association with inflammation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ying Yang, Meng Hong, Wen-Wen Lian and Zhi Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Project of Zhejiang Traditional Chinese Medicine Technology |
2018ZA063 |
| Chinese National Natural and Science Foundation |
81700552 |
| Natural Science Fund Committee of Zhejiang Province |
LQ20C200010 |
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| Corresponding Author |
Zhi Chen, Doctor, Academic Fellow, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou 310003, Zhejiang Province, China. zjuchenzhi@zju.edu.cn |
| Key Words |
Astragaloside IV; Pharmacological effect; Autophagy; Inflammation |
| Core Tip |
Astragaloside IV (AS-IV) is one of the main active ingredients of the aqueous extract Huangqi. Many experimental models have shown that AS-IV has broad beneficial effects on various diseases. This review demonstrates and summarizes the pharmacological effects and autophagic mechanism of AS-IV. The autophagic effects are associated with inflammation or not and multiple signalling pathways in experimental models. Based on this evidence, AS-IV will be used as replacement therapy for treating the above various diseases. |
| Publish Date |
2022-09-27 13:00 |
| Citation |
Yang Y, Hong M, Lian WW, Chen Z. Review of the pharmacological effects of astragaloside IV and its autophagic mechanism in association with inflammation. World J Clin Cases 2022; 10(28): 10004-10016 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i28/10004.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i28.10004 |
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