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9/27/2022 1:00:17 PM | Browse: 188 | Download: 522
Publication Name World Journal of Clinical Cases
Manuscript ID 77131
Country/Territory China
Received
2022-04-17 10:43
Peer-Review Started
2022-04-17 10:45
To Make the First Decision
Return for Revision
2022-05-13 01:44
Revised
2022-05-23 03:20
Second Decision
2022-08-24 02:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-08-25 17:49
Articles in Press
2022-08-25 17:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-08-22 17:04
Typeset the Manuscript
2022-09-07 07:43
Publish the Manuscript Online
2022-09-27 13:00
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology & Pharmacy
Manuscript Type Minireviews
Article Title Review of the pharmacological effects of astragaloside IV and its autophagic mechanism in association with inflammation
Manuscript Source Unsolicited Manuscript
All Author List Ying Yang, Meng Hong, Wen-Wen Lian and Zhi Chen
ORCID
Author(s) ORCID Number
Ying Yang http://orcid.org/0000-0002-5002-7960
Meng Hong http://orcid.org/0000-0002-1647-5516
Zhi Chen http://orcid.org/0000-0002-0848-1502
Funding Agency and Grant Number
Funding Agency Grant Number
Project of Zhejiang Traditional Chinese Medicine Technology 2018ZA063
Chinese National Natural and Science Foundation 81700552
Natural Science Fund Committee of Zhejiang Province LQ20C200010
Corresponding Author Zhi Chen, Doctor, Academic Fellow, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou 310003, China. zjuchenzhi@zju.edu.cn
Key Words Astragaloside IV; Pharmacological effect; Autophagy; Inflammation
Core Tip Astragaloside IV (AS-IV) is one of the main active ingredients of the aqueous extract Huangqi. Many experimental models have shown that AS-IV has broad beneficial effects on various diseases. This review demonstrates and summarizes the pharmacological effects and autophagic mechanism of AS-IV. The autophagic effects are associated with inflammation or not and multiple signalling pathways in experimental models. Based on this evidence, AS-IV will be used as replacement therapy for treating the above various diseases.
Publish Date 2022-09-27 13:00
Citation Yang Y, Hong M, Lian WW, Chen Z. Review of the pharmacological effects of astragaloside IV and its autophagic mechanism in association with inflammation. World J Clin Cases 2022; 10(28): 10004-10016
URL https://www.wjgnet.com/2307-8960/full/v10/i28/10004.htm
DOI https://dx.doi.org/10.12998/wjcc.v10.i28.10004
Full Article (PDF) WJCC-10-10004.pdf
Full Article (Word) WJCC-10-10004.docx
Manuscript File 77131_Auto_Edited-LM.docx
Answering Reviewers 77131-Answering reviewers.pdf
Audio Core Tip 77131-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 77131-Conflict-of-interest statement.pdf
Copyright License Agreement 77131-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 77131-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 77131-Language certificate.pdf
Peer-review Report 77131-Peer-review(s).pdf
Scientific Misconduct Check 77131-Bing-Wang DM-1.png
Scientific Misconduct Check 77131-CrossCheck.png
Scientific Editor Work List 77131-Scientific editor work list .pdf