Publication Name	World Journal of Diabetes
Manuscript ID	7742
Country	China

Received	2013-11-30 12:26
Peer-Review Started	2013-11-30 21:03
To Make the First Decision	2013-12-25 18:18
Return for Revision	2014-01-06 09:01
Revised
Second Decision	2014-03-04 09:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-04 10:27
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-17 17:42
Typeset the Manuscript	2014-04-11 09:51
Publish the Manuscript Online	2014-04-18 11:34

ISSN	1948-9358 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Physiology
Manuscript Type	Topic Highlights
Article Title	New insights into insulin: The anti-inflammatory effect and its clinical relevance
Manuscript Source	Invited Manuscript
All Author List	Qiang Sun, Jia Li and Feng Gao
Funding Agency and Grant Number	Funding Agency Grant Number State Key Program of National Natural Science Foundation of China 81030005 National High Technology Research and Development Program of China 2014AA020542 National Natural Science Foundation of China 31371150
Corresponding Author	Jia Li, PhD, Department of Physiology, School of Basic Medical Sciences, Fourth Military Medical University, 169 Changlexi Road, Xi’an 710032, Shannxi Province, China. jiali816@fmmu.edu.cn
Key Words	Insulin; Inflammation; Hyperglycemia
Core Tip	Hyperglycemia is closely correlated with poor outcomes of morbidity and mortality in critically ill patients. As the only glucose-lowering hormone in the body, insulin not only alleviates the detrimental effects of hyperglycemia through its metabolic regulation, but also directly modulates inflammatory mediators and acts upon immune cells to enhance immunocompetence. This review summarizes the recent advances regarding the anti-inflammatory effects of insulin from our laboratory as well as others, in the hope of leading to a better understanding of this old, classic and wonder hormone and its wider and effective applications in clinical practice.
Publish Date	2014-04-18 11:34
Citation	Sun Q, Li J, Gao F. New insights into insulin: The anti-inflammatory effect and its clinical relevance. World J Diabetes 2014; 5(2): 89-96
URL	http://www.wjgnet.com/1948-9358/full/v5/i2/89.htm
DOI	http://dx.doi.org/10.4239/wjd.v5.i2.89

Full Article (PDF)	WJD-5-89.pdf
Full Article (Word)	WJD-5-89.doc
Manuscript File	7742-Review.doc
Answering Reviewers	7742-Answering reviewers.pdf
Copyright License Agreement	7742-Copyright assignment.pdf
Peer-review Report	7742-Peer reviewer(s).pdf
Scientific Editor Work List	7742-Scientific editor work list.doc