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9/1/2014 11:47:00 AM | Browse: 1096 | Download: 904
Publication Name World Journal of Diabetes
Manuscript ID 7742
Country/Territory China
Received
2013-11-30 12:26
Peer-Review Started
2013-11-30 21:03
To Make the First Decision
2013-12-25 18:18
Return for Revision
2014-01-06 09:01
Revised
Second Decision
2014-03-04 09:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-03-04 10:27
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-03-17 17:42
Typeset the Manuscript
2014-04-11 09:51
Publish the Manuscript Online
2014-04-18 11:34
ISSN 1948-9358 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Physiology
Manuscript Type Topic Highlights
Article Title New insights into insulin: The anti-inflammatory effect and its clinical relevance
Manuscript Source Invited Manuscript
All Author List Qiang Sun, Jia Li and Feng Gao
Funding Agency and Grant Number
Funding Agency Grant Number
State Key Program of National Natural Science Foundation of China 81030005
National High Technology Research and Development Program of China 2014AA020542
National Natural Science Foundation of China 31371150
Corresponding Author Jia Li, PhD, Department of Physiology, School of Basic Medical Sciences, Fourth Military Medical University, 169 Changlexi Road, Xi’an 710032, Shannxi Province, China. jiali816@fmmu.edu.cn
Key Words Insulin; Inflammation; Hyperglycemia
Core Tip Hyperglycemia is closely correlated with poor outcomes of morbidity and mortality in critically ill patients. As the only glucose-lowering hormone in the body, insulin not only alleviates the detrimental effects of hyperglycemia through its metabolic regulation, but also directly modulates inflammatory mediators and acts upon immune cells to enhance immunocompetence. This review summarizes the recent advances regarding the anti-inflammatory effects of insulin from our laboratory as well as others, in the hope of leading to a better understanding of this old, classic and wonder hormone and its wider and effective applications in clinical practice.
Publish Date 2014-04-18 11:34
Citation Sun Q, Li J, Gao F. New insights into insulin: The anti-inflammatory effect and its clinical relevance. World J Diabetes 2014; 5(2): 89-96
URL http://www.wjgnet.com/1948-9358/full/v5/i2/89.htm
DOI http://dx.doi.org/10.4239/wjd.v5.i2.89
Full Article (PDF) WJD-5-89.pdf
Full Article (Word) WJD-5-89.doc
Manuscript File 7742-Review.doc
Answering Reviewers 7742-Answering reviewers.pdf
Copyright License Agreement 7742-Copyright assignment.pdf
Peer-review Report 7742-Peer reviewer(s).pdf
Scientific Editor Work List 7742-Scientific editor work list.doc