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9/23/2022 12:48:56 AM | Browse: 250 | Download: 597
Publication Name World Journal of Hepatology
Manuscript ID 77505
Country United States
Received
2022-05-05 12:56
Peer-Review Started
2022-05-05 12:58
To Make the First Decision
Return for Revision
2022-06-08 10:34
Revised
2022-06-20 03:41
Second Decision
2022-08-22 03:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-08-25 21:12
Articles in Press
2022-08-25 21:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-09-02 04:49
Publish the Manuscript Online
2022-09-23 00:48
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Heredity hemochromatosis: Temporal trends, sociodemographic characteristics, and independent risk factor of hepatocellular cancer – nationwide population-based study
Manuscript Source Unsolicited Manuscript
All Author List Maryam Bilal Haider, Ali Al Sbihi, Ahmed Jamal Chaudhary, Syed M Haider and Ahmed Iqbal Edhi
ORCID
Author(s) ORCID Number
Maryam Bilal Haider http://orcid.org/0000-0002-4157-8576
Ali Al Sbihi http://orcid.org/0000-0002-0685-8652
Ahmed Jamal Chaudhary http://orcid.org/0000-0001-8229-2331
Syed M Haider http://orcid.org/0000-0001-8693-9075
Ahmed Iqbal Edhi http://orcid.org/0000-0002-9193-1462
Funding Agency and Grant Number
Corresponding Author Maryam Bilal Haider, MD, Doctor, Department of Internal Medicine, Detroit Medical Center, Wayne State University, Sinai Grace Hospital, 6071 Outer Dr W, Detroit, MI 48235, United States. maryambilalhaider@yahoo.com
Key Words Heredity hemochromatosis; Hepatocellular carcinoma, Cirrhosis; Hepatitis; Diabetes mellitus; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Wilson disease; Alpha1-antitrypsin deficiency; Blood transfusion; Epidemiology; Demographics; Big data; Hospitalization
Core Tip Our study is a National Inpatient Sample -based study in which we aim to analyze heredity hemochromatosis (HH) patients’ characteristics, temporal trends, and sociodemographic characteristics over the last decade, in addition to studying this disease as an independent risk factor for developing hepatocellular cancer (HCC) without the stage of liver cirrhosis. Our large and diverse sample of about 18000 HH hospitalizations showed an increasing trend of inpatient admissions and costs with a similar length of hospital stay over the last decade. It also showed HH as an independent risk factor for HCC with an aOR close to 29 on multivariate analysis. We believe this will open the door for further retrospective and prospective studies to address disease trends and the understudied and independent relationship between HH and HCC in a large patient cohort.
Publish Date 2022-09-23 00:48
Citation Haider MB, Al Sbihi A, Chaudhary AJ, Haider SM, Edhi AI. Heredity hemochromatosis: Temporal trends, sociodemographic characteristics, and independent risk factor of hepatocellular cancer – nationwide population-based study. World J Hepatol 2022; 14(9): 1804-1816
URL https://www.wjgnet.com/1948-5182/full/v14/i9/1804.htm
DOI https://dx.doi.org/10.4254/wjh.v14.i9.1804
Full Article (PDF) WJH-14-1804.pdf
Full Article (Word) WJH-14-1804.docx
Manuscript File 77505_Auto_Edited-LJH-LS.docx
Answering Reviewers 77505-Answering reviewers.pdf
Audio Core Tip 77505-Audio core tip.m4a
Biostatistics Review Certificate 77505-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 77505-Conflict-of-interest statement.pdf
Copyright License Agreement 77505-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 77505-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 77505-Institutional review board statement.pdf
Supplementary Material 77505-Supplementary material.pdf
Peer-review Report 77505-Peer-review(s).pdf
Scientific Misconduct Check 77505-Bing-Liu JH-2.jpg
Scientific Misconduct Check 77505-CrossCheck.jpg
Scientific Editor Work List 77505-Scientific editor work list.pdf