Publication Name	World Journal of Diabetes
Manuscript ID	7759
Country	Italy

Received	2013-11-30 13:18
Peer-Review Started	2013-12-02 14:07
To Make the First Decision	2014-03-12 16:57
Return for Revision	2014-03-20 20:50
Revised	2014-04-10 20:13
Second Decision	2014-07-14 17:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-07-14 17:23
Articles in Press	2014-07-14 17:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-05 18:41
Publish the Manuscript Online	2014-08-17 13:16

ISSN	1948-9358 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Topic Highlights
Article Title	Hepatitis C virus infection and type 1 and type 2 diabetes mellitus
Manuscript Source	Invited Manuscript
All Author List	Alessandro Antonelli, Silvia Martina Ferrari, Dilia Giuggioli, Andrea Di Domenicantonio, Ilaria Ruffilli, Alda Corrado, Silvia Fabiani, Santino Marchi, Clodoveo Ferri, Ele Ferrannini and Poupak Fallahi
Funding Agency and Grant Number
Corresponding Author	Alessandro Antonelli, MD, Professor, Department of Clinical and Experimental Medicine, University of Pisa, Via Savi, 10, I-56126 Pisa, Italy. alessandro.antonelli@med.unipi.it
Key Words	Hepatitis C virus infection; Type 1 diabetes mellitus; Type 2 diabetes mellitus; Epidemiology; Pathogenesis; Prevention; Treatment
Core Tip	Many studies have shown an association between type 2 diabetes mellitus (T2DM) and chronic hepatitis C (CHC) infection. The processes through which CHC is associated with T2DM seem to involve direct viral effects, insulin resistance, proinflammatory cytokines, and chemokines. Few data have been reported on the association of CHC and T1DM. A small number of studies indicate that interferon-α therapy can induce T1DM. Diabetic CHC patients have an increased risk of developing cirrhosis and hepatocellular carcinoma compared with non-diabetics. Clinical trials on hepatitis C virus-positive patients have reported improvements in glucose metabolism after antiviral treatment.
Publish Date	2014-08-17 13:16
Citation	Antonelli A, Ferrari SM, Giuggioli D, Di Domenicantonio A, Ruffilli I, Corrado A, Fabiani S, Marchi S, Ferri C, Ferrannini E, Fallahi P. Hepatitis C virus infection and type 1 and type 2 diabetes mellitus. World J Diabetes 2014; 5(5): 586-600
URL	http://www.wjgnet.com/1948-9358/full/v5/i5/586.htm
DOI	http://dx.doi.org/10.4239/wjd.v5.i5.586

Full Article (PDF)	WJD-5-586.pdf
Full Article (Word)	WJD-5-586.doc
Manuscript File	7759-Review.doc
Answering Reviewers	7759-Answering reviewers.pdf
Copyright License Agreement	7759-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7759-Language certificate.pdf
Peer-review Report	7759-Peer review(s).pdf
Scientific Misconduct Check	7759-CrossCheck.jpg
Scientific Editor Work List	7759-Scientific editor work list.pdf