Publication Name	World Journal of Gastroenterology
Manuscript ID	77653
Country	China

Received	2022-05-25 14:20
Peer-Review Started	2022-05-25 14:23
To Make the First Decision
Return for Revision	2022-07-12 23:58
Revised	2022-07-23 16:35
Second Decision	2022-08-18 03:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-08-22 16:35
Articles in Press	2022-08-22 16:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-09-06 10:44
Publish the Manuscript Online	2022-09-15 13:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Basic Study
Article Title	Alcohol promotes epithelial mesenchymal transformation-mediated premetastatic niche formation of colorectal cancer by activating interaction between laminin-γ2 and integrin-β1
Manuscript Source	Unsolicited Manuscript
All Author List	Fei-Fei Nong, Yu-Qi Liang, Shang-Ping Xing, Yin-Fang Xiao, Hui-Hui Chen and Bin Wen
ORCID	Author(s) ORCID Number Fei-Fei Nong http://orcid.org/0000-0002-2306-0108 Yu-Qi Liang http://orcid.org/0000-0002-7481-116X Shang-Ping Xing http://orcid.org/0000-0001-7252-7176 Yin-Fang Xiao http://orcid.org/0000-0001-5196-641X Hui-Hui Chen http://orcid.org/0000-0002-0129-6718 Bin Wen http://orcid.org/0000-0001-9096-3115
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81673944
Corresponding Author	Bin Wen, PhD, Academic Research, Full Professor, Pi‐Wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, No. 232 Waihuandong Road, Guangzhou 510000, Guangdong , China. wenbin@gzucm.edu.cn
Key Words	Alcohol; Colorectal cancer; Premetastatic niche; Epithelial mesenchymal transformation; Metastasis
Core Tip	Our study indicated that alcohol promotes epithelial mesenchymal transformation-mediated premetastatic niche formation of colorectal cancer (CRC) by activating the early interaction between laminin γ2 and integrin β1 and lead to CRC metastasis.
Publish Date	2022-09-15 13:37
Citation	Nong FF, Liang YQ, Xing SP, Xiao YF, Chen HH, Wen B. Alcohol promotes epithelial mesenchymal transformation-mediated premetastatic niche formation of colorectal cancer by activating interaction between laminin γ2 and integrin β1. World J Gastroenterol 2022; 28(35): 5154-5174
URL	https://www.wjgnet.com/1007-9327/full/v28/i35/5154.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i35.5154

Full Article (PDF)	WJG-28-5154.pdf
Full Article (Word)	WJG-28-5154.docx
Manuscript File	77653_Auto_Edited-LM.docx
Answering Reviewers	77653-Answering reviewers.pdf
Audio Core Tip	77653-Audio core tip.m4a
Biostatistics Review Certificate	77653-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	77653-Conflict-of-interest statement.pdf
Copyright License Agreement	77653-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	77653-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	77653-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	77653-Language certificate.pdf
Peer-review Report	77653-Peer-review(s).pdf
Scientific Editor Work List	77653-Scientific editor work list.pdf