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9/23/2022 9:45:22 AM | Browse: 281 | Download: 675
Publication Name World Journal of Stem Cells
Manuscript ID 77709
Country/Territory China
Received
2022-05-18 09:12
Peer-Review Started
2022-05-18 09:15
To Make the First Decision
Return for Revision
2022-06-23 16:07
Revised
2022-07-07 02:59
Second Decision
2022-09-02 03:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-09-07 23:51
Articles in Press
2022-09-07 23:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-09-22 00:32
Publish the Manuscript Online
2022-09-23 09:45
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Strategies to improve the effect of mesenchymal stem cell therapy on inflammatory bowel disease
Manuscript Source Unsolicited Manuscript
All Author List Meng-Yue Shi, Lian Liu and Fu-Yuan Yang
ORCID
Author(s) ORCID Number
Meng-Yue Shi http://orcid.org/0000-0002-3890-8335
Fu-Yuan Yang http://orcid.org/0000-0001-9179-195X
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Research Project of Hubei Province 2021CFB210
Corresponding Author Fu-Yuan Yang, PhD, Lecturer, Health Science Center, Yangtze University, No. 1 Xueyuan Road, Jingzhou 434020, Hubei Province, China. ivansblue@sina.com
Key Words Mesenchymal stem cells; Inflammatory bowel diseases; Inflammation; Pretreatment; Gene editing
Core Tip Mesenchymal stem cell (MSC) transplantation is a novel treatment method for inflammatory bowel disease (IBD) that has exhibits certain achievements in clinical trials. Here, we reviewed the developed strategies for enhancing the therapeutic effect of MSCs, and among these, pretreatment with MSCs is the most common method. The pretreatments include bioactive substances, hypoxia and modification of culture methods and are able to enhance the migration ability of MSCs to repair the damaged intestinal mucosa or upregulate the expression of cytokines. These methods provide new ideas for the future clinical application of MSCs in the treatment of IBD.
Publish Date 2022-09-23 09:45
Citation Shi MY, Liu L, Yang FY. Strategies to improve the effect of mesenchymal stem cell therapy on inflammatory bowel disease. World J Stem Cells 2022; 14(9): 684-699
URL https://www.wjgnet.com/1948-0210/full/v14/i9/684.htm
DOI https://dx.doi.org/10.4252/wjsc.v14.i9.684
Full Article (PDF) WJSC-14-684.pdf
Full Article (Word) WJSC-14-684.docx
Manuscript File 77709_Auto_Edited-LS.docx
Answering Reviewers 77709-Answering reviewers.pdf
Audio Core Tip 77709-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 77709-Conflict-of-interest statement.pdf
Copyright License Agreement 77709-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 77709-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 77709-Language certificate.pdf
Peer-review Report 77709-Peer-review(s).pdf
Scientific Misconduct Check 77709-Bing-Wang JJ-2.png
Scientific Editor Work List 77709-Scientific editor work list.pdf