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Articles Published Processes
9/16/2022 11:52:44 AM | Browse: 285 | Download: 781
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Received |
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2022-05-17 02:42 |
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Peer-Review Started |
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2022-05-17 02:44 |
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To Make the First Decision |
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Return for Revision |
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2022-06-16 08:11 |
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Revised |
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2022-06-24 15:59 |
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Second Decision |
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2022-08-19 03:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-08-21 17:54 |
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Articles in Press |
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2022-08-21 17:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-08-14 11:01 |
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Typeset the Manuscript |
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2022-09-02 06:28 |
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Publish the Manuscript Online |
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2022-09-16 11:52 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Concurrent severe hepatotoxicity and agranulocytosis induced by Polygonum multiflorum: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
You-Lin Shao, Chun-Ming Ma, Jian-Ming Wu, Feng-Cai Guo and Suo-Cai Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Applied Basic Research Project of Changzhou |
CJ20190080 |
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| Corresponding Author |
You-Lin Shao, MD, Chief Physician, Department of Hepatology, Changzhou Third People's Hospital, No. 300 North Lanling Road, Changzhou 213001, Jiangsu Province, China. syl84289@aliyun.com |
| Key Words |
Polygonum multiflorum; Hepatotoxicity; Agranulocytosis; Case report |
| Core Tip |
Polygonum multiflorum is a common traditional Chinese medicine and is commonly used as a dietary supplement. However, severe idiosyncratic hepatotoxicity in certain individuals has been reported. Moreover, if idiosyncratic agranulocytosis occurs simultaneously, it may be fatal. Roussel Uclaf Causality Assessment Method scale and Naranjo algorithm are useful tools for the assessment of drug-induced liver injury and adverse drug reactions, respectively. Early discontinuation can prevent disease progression, facilitating recovery. The combination therapy of glucocorticoids, anti-inflammatory medications, and liver protection is beneficial for idiosyncratic drug reactions. |
| Publish Date |
2022-09-16 11:52 |
| Citation |
Shao YL, Ma CM, Wu JM, Guo FC, Zhang SC. Concurrent severe hepatotoxicity and agranulocytosis induced by Polygonum multiflorum: A case report. World J Clin Cases 2022; 10(27): 9921-9928 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i27/9921.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i27.9921 |
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