Publication Name	World Journal of Gastroenterology
Manuscript ID	7781
Country	Japan

Received	2013-11-30 14:25
Peer-Review Started	2013-12-01 07:36
First Decision by Editorial Office Director
Return for Revision	2014-01-20 21:56
Revised	2014-02-14 15:48
Publication Fee Transferred
Second Decision by Editor	2014-05-19 08:56
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-05-19 09:15
Articles in Press	2014-05-23 09:48
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-01 15:15
Publish the Manuscript Online	2014-11-10 19:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Prevention of esophageal strictures after endoscopic submucosal dissection
Manuscript Source	Invited Manuscript
All Author List	Shinichiro Kobayashi, Nobuo Kanai, Takeshi Ohki, Ryo Takagi, Naoyuki Yamaguchi, Hajime Isomoto, Yoshiyuki Kasai, Takahiro Hosoi, Kazuhiko Nakao, Susumu Eguchi, Masakazu Yamamoto, Masayuki Yamato and Teruo Okano
Funding Agency and Grant Number	Funding Agency Grant Number Creation of Innovation Centers for Advanced Interdisciplinary Research Areas Program that was part of the Project for Developing Innovation Systems by the Cell Sheet Tissue Engineering Center from the Ministry of Education, Culture, Sports, Science and Technology, Japan
Corresponding Author	Teruo Okano, PhD, Institute of Advanced Biomedical Engineering and Science, Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan. tokano@abmes.twmu.ac.jp
Key Words	Endoscopic submucosal dissection; Esophageal stricture; Systemic steroid therapy; Autologous oral mucosal epithelial cell sheet
Core Tip	Esophageal strictures after extensive endoscopic submucosal dissection (ESD) reduce quality of life. Endoscopic local injections and the oral administration of steroids are safe and effective for preventing esophageal strictures. In addition, several tissue engineering therapies have been used in attempts to overcome severe esophageal strictures. Cell-based tissue engineering therapy with fabricated autologous oral mucosal epithelial cell sheets has been used to prevent esophageal strictures after ESD in nine patients. This therapy has been shown to be safe and may be widely used in the future.
Publish Date	2014-11-10 19:10
Citation	Kobayashi S, Kanai N, Ohki T, Takagi R, Yamaguchi N, Isomoto H, Kasai Y, Hosoi T, Nakao K, Eguchi S, Yamamoto M, Yamato M, Okano T. Prevention of esophageal strictures after endoscopic submucosal dissection. World J Gastroenterol 2014; 20(41): 15098-15109
URL	http://www.wjgnet.com/1007-9327/full/v20/i41/15098.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i41.15098

Full Article (PDF)	WJG-20-15098.pdf
Full Article (Word)	WJG-20-15098.doc
Manuscript File	7781-Review.docx
Answering Reviewers	7781-Answering reviewers.pdf
Copyright License Agreement	7781-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7781-Language certificate.pdf
Peer-review Report	7781-Peer review(s).pdf