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Articles Published Processes
9/7/2022 8:29:04 AM | Browse: 504 | Download: 976
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Received |
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2022-05-30 13:03 |
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Peer-Review Started |
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2022-05-30 13:05 |
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To Make the First Decision |
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Return for Revision |
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2022-06-18 18:54 |
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Revised |
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2022-07-16 05:56 |
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Second Decision |
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2022-08-08 03:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-08-17 21:37 |
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Articles in Press |
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2022-08-17 21:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-08-28 23:47 |
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Publish the Manuscript Online |
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2022-09-07 08:29 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Efficacy of cytapheresis in patients with ulcerative colitis showing insufficient or lost response to biologic therapy
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Manuscript Source |
Invited Manuscript |
All Author List |
Masahiro Iizuka, Takeshi Etou and Shiho Sagara |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Masahiro Iizuka, MD, PhD, Director, Director, Doctor, Doctor, Akita Health Care Center, Akita Red Cross Hospital, 3-4-23 Nakadori, Akita 010-0001, Japan. maiizuka@woody.ocn.ne.jp |
Key Words |
Ulcerative colitis; Inflammatory bowel disease; Cytapheresis; Granulocyte and monocyte adsorptive apheresis; Anti-tumor necrosis factor-α antibody; Combination therapy |
Core Tip |
Management of refractory ulcerative colitis (UC) experiencing primary non-response or loss of response to biologics is a critical issue. We first summarized the efficacy of cytapheresis (CAP) for such patients. Although CAP tended to have lower effects for induction of remission in patients with UC who were refractory to biologics, combination therapies with CAP and biologics induced clinical remission or response in more than 40% of such patients with UC on average. Given the excellent safety profile of CAP, we believe that this combination therapy can be an alternative therapeutic strategy for such refractory UC patients. |
Publish Date |
2022-09-07 08:29 |
Citation |
Iizuka M, Etou T, Sagara S. Efficacy of cytapheresis in patients with ulcerative colitis showing insufficient or lost response to biologic therapy. World J Gastroenterol 2022; 28(34): 4959-4972 |
URL |
https://www.wjgnet.com/1007-9327/full/v28/i34/4959.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v28.i34.4959 |
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