Publication Name	World Journal of Gastroenterology
Manuscript ID	7797
Country	United Kingdom

Received	2013-11-30 15:10
Peer-Review Started	2013-11-30 21:12
To Make the First Decision	2014-01-09 18:38
Return for Revision	2014-01-20 21:57
Revised
Second Decision	2014-03-19 13:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-19 15:25
Articles in Press	2014-05-23 09:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-07 13:58
Publish the Manuscript Online	2014-08-20 18:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Emerging role of the KRAS-PDK1 axis in pancreatic cancer
Manuscript Source	Invited Manuscript
All Author List	Riccardo Ferro and Marco Falasca
Funding Agency and Grant Number
Corresponding Author	Marco Falasca, Professor, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Blizard Institute, Inositide Signalling Group, 4 Newark Street, London E1 2AT, United Kingdom. m.falasca@qmul.ac.uk
Key Words	Pancreatic cancer; Signal transduction; KRAS; Phosphoinositide 3-kinase; 3-phosphoinositide-dependent protein kinase 1
Core Tip	Recent evidence suggests that protein kinase 1 (PDK1) is a key oncogenic driver in pancreatic cancer. Furthermore, PDK1 appears to be activated downstream the main pancreatic cancer oncogene KRAS that is mutated in nearly all pancreatic adenocarcinomas. This evidence suggests that PDK1 could represent a novel target in the treatment of pancreatic cancer.
Publish Date	2014-08-20 18:38
Citation	Ferro R, Falasca M. Emerging role of the KRAS-PDK1 axis in pancreatic cancer. World J Gastroenterol 2014; 20(31): 10752-10757
URL	http://www.wjgnet.com/1007-9327/full/v20/i31/10752.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i31.10752

Full Article (PDF)	WJG-20-10752.pdf
Full Article (Word)	WJG-20-10752.doc
Manuscript File	7797-Review.docx
Answering Reviewers	7797-Answering reviewers.PDF
Copyright License Agreement	7797-Copyright assignment.PDF
Peer-review Report	7797-Peer review(s).pdf
Scientific Editor Work List	7797-Scientific editor work list.doc