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Articles Published Processes
9/23/2022 12:48:56 AM | Browse: 386 | Download: 884
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Received |
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2022-05-30 13:56 |
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Peer-Review Started |
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2022-05-30 14:00 |
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To Make the First Decision |
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Return for Revision |
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2022-07-13 22:55 |
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Revised |
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2022-07-18 10:05 |
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Second Decision |
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2022-08-08 03:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-08-18 00:11 |
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Articles in Press |
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2022-08-18 00:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-08-19 02:33 |
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Publish the Manuscript Online |
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2022-09-23 00:48 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Bile acids as drivers and biomarkers of hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Santo Colosimo and Jeremy W Tomlinson |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jeremy W Tomlinson, FRCP, PhD, Professor, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, NIHR Oxford Biomedical Research Centre, Churchill Hospital, Oxford OX3 7LE, United Kingdom. jeremy.tomlinson@ocdem.ox.ac.uk |
| Key Words |
Bile acid; Liver cancer; Screening; Cirrhosis; Serum metabolites; Urine metabolites |
| Core Tip |
The rapidly increasing prevalence of hepatocellular carcinoma (HCC) highlights the unmet clinical need to develop and enhance early diagnostic strategies. Evidence from rodent and in vitro models suggests that bile acids may have a crucial role in the pathogenesis of HCC. Changes in circulating bile acid profiles are observed in patients with HCC. Serum and urine bile acid profiles may predict HCC risk and may have potential as a non-invasive screening tool. |
| Publish Date |
2022-09-23 00:48 |
| Citation |
Colosimo S, Tomlinson J. Bile acids as drivers and biomarkers of hepatocellular carcinoma. World J Hepatol 2022;14(9): 1730-1738 |
| URL |
https://www.wjgnet.com/1948-5182/full/v14/i9/1730.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v14.i9.1730 |
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