Publication Name	World Journal of Stem Cells
Manuscript ID	78194
Country	China

Received	2022-06-13 06:27
Peer-Review Started	2022-06-13 06:30
To Make the First Decision
Return for Revision	2022-06-23 15:41
Revised	2022-07-05 09:35
Second Decision	2022-09-08 03:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-09-10 04:28
Articles in Press	2022-09-10 04:28
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-09-06 01:51
Typeset the Manuscript	2023-04-27 01:53
Publish the Manuscript Online	2023-05-26 11:17

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Dermatology
Manuscript Type	Basic Study
Article Title	Exosomes from circ-Astn1-modified adipose-derived mesenchymal stem cells enhance wound healing through miR-138-5p/SIRT1/FOXO1 axis regulation
Manuscript Source	Unsolicited Manuscript
All Author List	Zhi Wang, Cheng Feng, Hao Liu, Tian Meng, Wei-Qing Huang, Ke-Xin Song and You-Bin Wang
ORCID	Author(s) ORCID Number Zhi Wang http://orcid.org/0000-0001-6116-2992 Cheng Feng http://orcid.org/0000-0001-5603-5681 Hao Liu http://orcid.org/0000-0003-0423-6304 Tian Meng http://orcid.org/0000-0003-1289-0031 Wei-Qing Huang http://orcid.org/0000-0002-2123-8830 Ke-Xin Song http://orcid.org/0000-0003-4614-589X You-Bin Wang http://orcid.org/0000-0001-5373-2633
Funding Agency and Grant Number	Funding Agency Grant Number The Beijing Municipal Natural Science Foundation 7192160
Corresponding Author	Zhi Wang, MD, Doctor, Department of Plastic and Cosmetic Surgery, Peking Union Medical College Hospital, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. wzben@outlook.com
Key Words	Adipose-derived mesenchymal stem cells; Circ-Astn1; Diabetic; Exosomes; Angiogenesis
Core Tip	Circ-Astn1 promoted the therapeutic effect of adipose-derived mesenchymal stem cells-exosomes and thus improved wound healing in diabetes via miR-138-5p absorption and SIRT1 upregulation. Based on our data, we advocate targeting the circ-Astn1/miR-138-5p/SIRT1 axis as a potential therapeutic alternative for diabetic ulcers.
Publish Date	2023-05-26 11:17
Citation	Wang Z, Feng C, Liu H, Meng T, Huang WQ, Song KX, Wang YB. Exosomes from circ-Astn1-modified adipose-derived mesenchymal stem cells enhance wound healing through miR-138-5p/SIRT1/FOXO1 axis regulation. World J Stem Cells 2022; 15(5): 476-489
URL	https://www.wjgnet.com/1948-0210/full/v15/i5/476.htm
DOI	https://dx.doi.org/10.4252/wjsc.v15.i5.476

Full Article (PDF)	WJSC-15-476.pdf
Full Article (Word)	WJSC-15-476.docx
Manuscript File	78194_Auto_Edited-LM.docx
Answering Reviewers	78194-Answering reviewers.pdf
Audio Core Tip	78194-Audio core tip.mp3
Biostatistics Review Certificate	78194-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	78194-Conflict-of-interest statement.pdf
Copyright License Agreement	78194-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	78194-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	78194-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	78194-Language certificate.pdf
Peer-review Report	78194-Peer-review(s).pdf
Scientific Misconduct Check	78194-Bing-Fan JR-2.png
Scientific Editor Work List	78194-Scientific editor work list.pdf