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Articles Published Processes
9/20/2022 11:01:13 AM | Browse: 460 | Download: 930
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Received |
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2022-06-16 20:21 |
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Peer-Review Started |
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2022-06-16 20:25 |
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To Make the First Decision |
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Return for Revision |
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2022-07-13 05:05 |
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Revised |
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2022-07-20 20:27 |
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Second Decision |
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2022-08-08 03:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-08-17 23:49 |
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Articles in Press |
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2022-08-17 23:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-09-07 13:48 |
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Publish the Manuscript Online |
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2022-09-20 11:01 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Why do we not reverse the path? Stress can cause depression, reduction of brain-derived neurotrophic factor and increased inflammation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Angelo Emilio Claro, Clelia Palanza, Marianna Mazza, Alessandro Rizzi, Linda Tartaglione, Giuseppe Marano, Giovanna Muti-Schuenemann, Marta Rigoni, Paola Muti, Alfredo Pontecorvi, Luigi Janiri, Gabriele Sani and Dario Pitocco |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marianna Mazza, MD, PhD, Assistant Professor, Department of Geriatrics, Neuroscience and Orthopedics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy. marianna.mazza@policlinicogemelli.it |
| Key Words |
Depression; Inflammation; Brain-derived neurotrophic factor; Type 2 diabetes mellitus; Dementia; Psychological stress |
| Core Tip |
This paper proposes a distinct interpretation of the link that exists between increased inflammation and reduction of brain-derived neurotrophic factor (BDNF). We describe why most of the people with altered inflammatory status and low BDNF do not automatically have depression, and why some people become depressed without diverging from average serum levels of these markers. We also suggest a reason why the use of tumor necrosis factor-α inhibition has no effect as a therapy in patients with resistant depression and high inflammatory levels. |
| Publish Date |
2022-09-20 11:01 |
| Citation |
Claro AE, Palanza C, Mazza M, Rizzi A, Tartaglione L, Marano G, Muti-Schuenemann G, Rigoni M, Muti P, Pontecorvi A, Janiri L, Sani G, Pitocco D. Why do we not reverse the path? Stress can cause depression, reduction of brain-derived neurotrophic factor and increased inflammation. World J Psychiatry 2022; 12(9): 1264-1267 |
| URL |
https://www.wjgnet.com/2220-3206/full/v12/i9/1264.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v12.i9.1264 |
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