| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Neoadjuvant therapy in resectable pancreatic cancer: A promising curative method to improve the prognosis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hao-Qi Zhang, Jing Li, Chun-Lu Tan, Yong-Hua Chen, Zhen-Jiang Zheng and Xu-Bao Liu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University |
ZY2017302 1-3-5 |
| Key Research and Development Projects of Sichuan Province |
2019YFS0042 |
| Post-Doctor Research Project, West China Hospital, Sichuan University |
2020HXBH168 |
| Key R&D Project of Science and Technology Department of Sichuan Province |
2021YFS0107 |
|
| Corresponding Author |
Chun-Lu Tan, MD, PhD, Associate Professor, Surgeon, Department of Pancreatic Surgery, West China Hospital, Sichuan University, No. 37, Guoxue Lane, Wuhou District, Chengdu 610041, Sichuan Province, China. chunlutan@163.com |
| Key Words |
Neoadjuvant therapy; Resectable; Pancreatic cancer; Prognosis |
| Core Tip |
In this review, we collated data about risk factors influencing the prognoses of patients with resectable pancreatic cancer from five randomized controlled trials (RCTs) and discussed the possible reasons for the varying outcomes. By comparing the overall survival of two RCTs, we speculated that neoadjuvant therapy might actually benefit patients with low-risk factors for long-term survival. Moreover, we addressed some suggestions for the RCTs in the future. |
| Publish Date |
2022-10-14 12:54 |
| Citation |
Zhang HQ, Li J, Tan CL, Chen YH, Zheng ZJ, Liu XB. Neoadjuvant therapy in resectable pancreatic cancer: A promising curative method to improve prognosis. World J Gastrointest Oncol 2022; 14(10): 1903-1917 |
| URL |
https://www.wjgnet.com/1948-5204/full/v14/i10/1903.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v14.i10.1903 |
