BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
10/27/2022 4:55:04 AM | Browse: 296 | Download: 579
 |
Received |
|
2022-06-23 04:02 |
|
Peer-Review Started |
|
2022-06-23 04:05 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2022-09-05 02:22 |
|
Revised |
|
2022-09-14 15:28 |
|
Second Decision |
|
2022-09-29 03:37 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2022-09-29 10:48 |
|
Articles in Press |
|
2022-09-29 10:48 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2022-10-17 14:13 |
|
Publish the Manuscript Online |
|
2022-10-27 04:55 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Screening of traditional Chinese medicine monomers as ribonucleotide reductase M2 inhibitors for tumor treatment
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ya-Ya Qin, Song Feng, Xiao-Dong Zhang and Bin Peng |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Nanchong City school science and technology strategic cooperation |
20SXQT0304 |
| Research and development project plan of Affiliated Hospital of North Sichuan Medical College |
2020ZD003 |
|
| Corresponding Author |
Bin Peng, MD, Professor, School of Basic Medicine, North Sichuan Medical College, No. 234 Fujiang Road, Shunqing District, Nanchong 637000, Sichuan Province, China. binpeng01@sina.com |
| Key Words |
Tumor; Ribonucleotide reductase M2 inhibitor; Traditional Chinese medicine; Monomer; Molecular docking; Literature mining |
| Core Tip |
Tumors seriously threaten human life and health. In our work, we found that ribonucleotide reductase M2 (RRM2) is highly expressed in most tumor tissues, and is related to poor prognosis. Seven traditional Chinese medicine monomers with good binding ability to RRM2 were identified, and their binding sites were summarized and analyzed. Those will provide ideas for the development of anti-tumor drugs with RRM2 inhibition in the future. |
| Publish Date |
2022-10-27 04:55 |
| Citation |
Qin YY, Feng S, Zhang XD, Peng B. Screening of traditional Chinese medicine monomers as ribonucleotide reductase M2 inhibitors for tumor treatment. World J Clin Cases 2022; 10(31): 11299-11312 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i31/11299.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i31.11299 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
