| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Atherogenic index of plasma combined with waist circumference and body mass index to predict metabolic-associated fatty liver disease
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shao-Jie Duan, Zhi-Ying Ren, Tao Zheng, Hong-Ye Peng, Zuo-Hu Niu, Hui Xia, Jia-Liang Chen, Yuan-Chen Zhou, Rong-Rui Wang and Shu-Kun Yao |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Shu-Kun Yao, MD, Professor, Department of Gastroenterology, China-Japan Friendship Hospital, No. 2 Yinghua East Street, Chaoyang District, Beijing 100029, China. shukunyao@126.com |
| Key Words |
Atherogenic index of plasma; Metabolic-associated fatty liver disease; Receiver operating characteristic curve; Predictor |
| Core Tip |
Metabolic-associated fatty liver disease (MAFLD) is the most common chronic liver disease, and early identification of MAFLD is urgent. This study demonstrated that the atherogenic index of plasma was strongly and positively associated with the risk of MAFLD, and it can be a reference predictor for MAFLD. Then, we pioneered a novel noninvasive prediction model, A-W-B, combining atherogenic index of plasma, waist circumference, and body mass index and validated its excellent predictive performance for MAFLD. Furthermore, we also pointed out the optimal cutoff values of the A-W-B model to predict MAFLD in males and females, which will facilitate early clinical identification of MAFLD in different sex populations. This study is highly innovative, and the noninvasive prediction model, A-W-B, is convenient, affordable, and easy to obtain, which can provide better services for clinical prediction and screening of MAFLD and metabolic-related diseases. |
| Publish Date |
2022-09-23 10:13 |
| Citation |
Duan SJ, Ren ZY, Zheng T, Peng HY, Niu ZH, Xia H, Chen JL, Zhou YC, Wang RR, Yao SK. Atherogenic index of plasma combined with waist circumference and body mass index to predict metabolic-associated fatty liver disease. World J Gastroenterol 2022; 28(36): 5364-5379 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i36/5364.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i36.5364 |
