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11/16/2022 11:26:06 AM | Browse: 265 | Download: 877
Publication Name World Journal of Gastroenterology
Manuscript ID 78506
Country/Territory China
Received
2022-07-12 09:06
Peer-Review Started
2022-07-12 09:10
To Make the First Decision
Return for Revision
2022-09-26 07:45
Revised
2022-10-04 07:43
Second Decision
2022-11-03 03:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-11-03 20:58
Articles in Press
2022-11-03 20:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-11-14 08:33
Publish the Manuscript Online
2022-11-16 11:26
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Differential analysis of intestinal microbiota and metabolites in mice with dextran sulfate sodium-induced colitis
Manuscript Source Unsolicited Manuscript
All Author List Jia-Li Wang, Xiao Han, Jun-Xiang Li, Rui Shi, Lei-Lei Liu, Kai Wang, Yu-Ting Liao, Hui Jiang, Yang Zhang, Jun-Cong Hu, Li-Ming Zhang and Lei Shi
ORCID
Author(s) ORCID Number
Jia-Li Wang http://orcid.org/0000-0002-2789-5081
Xiao Han http://orcid.org/0000-0003-1340-9692
Jun-Xiang Li http://orcid.org/0000-0001-7590-9444
Rui Shi http://orcid.org/0000-0002-9374-0897
Lei-Lei Liu http://orcid.org/0000-0003-4639-5370
Kai Wang http://orcid.org/0000-0001-5510-7719
Yu-Ting Liao http://orcid.org/0000-0003-1821-048X
Hui Jiang http://orcid.org/0000-0003-3755-8975
Yang Zhang http://orcid.org/0000-0002-2704-9846
Jun-Cong Hu http://orcid.org/0000-0002-2493-5535
Li-Ming Zhang http://orcid.org/0000-0003-2039-7124
Lei Shi http://orcid.org/0000-0002-7925-5166
Funding Agency and Grant Number
Funding Agency Grant Number
13th Five-Year Plan for National Key R&D Program of China 2018YFC1705405
Scientific Research Innovation Team Project of Beijing University of Chinese Medicine 2019-JYB-TD004
New Faculty Startup Fund Program of BUCM 2022-JYB-XJSJJ078
National Natural Science Foundation of China 82004113
Corresponding Author Lei Shi, MD, PhD, Research Assistant, Research Associate, Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, No. 6 Fangxingyuan Zone 1, Fangzhuang, Fengtai District, Beijing 100078, China. b01350@bucm.edu.cn
Key Words Ulcerative colitis; Gut microbiota; Metabolites; Dextran sulfate sodium; Mucin
Core Tip We observed that the differences in microbiota and their metabolites can cause different degrees of colitis. The differential metabolites of the microbiota in colitis are mainly enriched in pathways related to the key structural sequence synthesis of mucin, and the different levels of the metabolites lead to differential expression of mucin and mucus. Therefore, the differential metabolites of colitis could regulate the composition and function of mucus. In addition, the differential intestinal microbiota and their metabolites in mice with colitis were largely associated with amino acid and energy metabolism.
Publish Date 2022-11-16 11:26
Citation Wang JL, Han X, Li JX, Shi R, Liu LL, Wang K, Liao YT, Jiang H, Zhang Y, Hu JC, Zhang LM, Shi L. Differential analysis of intestinal microbiota and metabolites in mice with dextran sulfate sodium-induced colitis. World J Gastroenterol 2022; 28(43): 6109-6130
URL https://www.wjgnet.com/1007-9327/full/v28/i43/6109.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i43.6109
Full Article (PDF) WJG-28-6109.pdf
Full Article (Word) WJG-28-6109.docx
The ARRIVE Guidelines 78506-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 78506_Auto_Edited-LM.docx
Answering Reviewers 78506-Answering reviewers.pdf
Audio Core Tip 78506-Audio core tip.mp3
Biostatistics Review Certificate 78506-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 78506-Conflict-of-interest statement.pdf
Copyright License Agreement 78506-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 78506-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 78506-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate 78506-Language certificate.pdf
Peer-review Report 78506-Peer-review(s).pdf
Scientific Editor Work List 78506-Scientific editor work list.pdf