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Articles Published Processes
11/4/2022 5:24:37 AM | Browse: 605 | Download: 1288
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Received |
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2022-07-28 05:56 |
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Peer-Review Started |
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2022-07-28 05:59 |
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First Decision by Editorial Office Director |
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2022-08-31 21:07 |
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Return for Revision |
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2022-08-31 21:07 |
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Revised |
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2022-09-17 07:39 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-10-25 03:31 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-10-27 17:11 |
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Articles in Press |
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2022-10-27 17:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-10-31 01:06 |
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Publish the Manuscript Online |
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2022-11-04 05:24 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Esophageal Lichen Planus: Current Knowledge, Challenges and Future Perspectives
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Annegrit Decker, Franziska Schauer, Adhara Lazaro, Carmen Monasterio, Arthur Robert Schmidt, Annette Schmitt-Graeff and Wolfgang Kreisel |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wolfgang Kreisel, MD, Emeritus Professor, Department of Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Diseases,, Faculty of Medicine, Medical Center - University of Freiburg, Hugstetter Str. 55, Freiburg 79106, Germany. wolfgang.kreisel@uniklinik-freiburg.de |
| Key Words |
Lichen planus; Esophagitis; T-lymphocytes; Budesonide; Dysphagia; Precancerosis |
| Core Tip |
Lichen planus is a frequent, chronic inflammatory disease involving the skin, mucous membranes and/or skin appendages. Esophageal involvement in lichen planus (ELP) is an underdiagnosed inflammatory condition. ELP mainly affects middle-aged women. The principal symptom is dysphagia. Aymptomatic cases may occur. An immune-mediated pathogenesis is probable. Endoscopy shows mucosal denudation and tearing, trachealization, and hyperkeratosis. Scarring esophageal stenosis occurs. Histology includes mucosal detachment, T-lymphocytic infiltrations, epithelial apoptosis, dyskeratosis, and hyperkeratosis. Direct immuno-fluorescence shows fibrinogen deposits along the basement membrane zone. Treatment with topical steroids or immunosuppression may induce symptomatic and histologic improvement. ELP can be regarded as a precancerous condition. |
| Publish Date |
2022-11-04 05:24 |
| Citation |
Decker A, Schauer F, Lazaro A, Monasterio C, Schmidt AR, Schmitt-Graeff A, Kreisel W. Esophageal lichen planus: Current knowledge, challenges and future perspectives. World J Gastroenterol 2022; 28(41): 5893-5909 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i41/5893.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i41.5893 |
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