| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Retrospective Study |
| Article Title |
Dynamic changes of estimated glomerular filtration rate are conversely related to triglyceride in non-overweight patients
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Si-Qi Liu, Xiu-Jun Zhang, Yuan Xue, Rui Huang, Jian Wang, Chao Wu, Yi-Shan He, Ya-Ru Pan and Long-Gen Liu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the 333 High-level Talents Project of Jiangsu Province |
No. LGY2020032 |
| the Science and Technology Project of Changzhou |
No. CJ20200057 |
| Qingmiao Talents Cultivation Project of Changzhou Health Commission |
No. CZQM2020089 |
|
| Corresponding Author |
Long-Gen Liu, MD, Chief Doctor, Dean, Doctor, Doctor, Professor, Institute of Hepatology, The Third People’s Hospital of Changzhou, No. 300 Lanling North Road, Changzhou 213000, Jiangsu Province, China. ssewllg@163.com |
| Key Words |
Tenofovir disoproxil fumarate; Hepatitis B virus; Glomerular filtration rate; Overweight; Body mass index |
| Core Tip |
Correlation between Triglyceride (TG) and estimated glomerular filtration rate (eGFR) remains largely unknown. Our study indicated that more patients in non-overweight group achieved alanine aminotransferase normalization compared with those in overweight group (χ2 = 11.036, P < 0.01). In non-overweight patients, TG was negatively correlated with GFR at the four-time points (P = 0.002, 0.030, 0.007, 0.008, respectively). Dynamic changes in renal function were conversely related to TG during TDF treatment in patients with CHB and normal BMI, but not with overweight. Age [P < 0.01, 95%CI (0.97–1.005)] and baseline eGFR [P < 0.01, 95%CI (5.056–33.668)] were independent risk factors for eGFR < 90 mL/(min·1.73 m2) at the 3rd year. |
| Publish Date |
2022-10-27 04:55 |
| Citation |
Liu SQ, Zhang XJ, Xue Y, Huang R, Wang J, Wu C, He YS, Pan YR, Liu LG. Dynamic changes of estimated glomerular filtration rate are conversely related to triglyceride in non-overweight patients. World J Clin Cases 2022; 10(31): 11371-11380 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i31/11371.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i31.11371 |
