Publication Name	World Journal of Virology
Manuscript ID	79220
Country	Thailand

Received	2022-08-09 21:20
Peer-Review Started	2022-08-09 21:23
To Make the First Decision
Return for Revision	2022-08-31 16:41
Revised	2022-09-21 21:34
Second Decision	2022-10-19 03:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-10-19 17:46
Articles in Press	2022-10-19 17:46
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-11-06 13:30
Typeset the Manuscript	2022-11-17 00:48
Publish the Manuscript Online	2022-11-23 13:56

ISSN	2220-3249 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Cholestatic liver injury: A rare but fatal complication during and after COVID-19 infection
Manuscript Source	Invited Manuscript
All Author List	Wachira Wongtanasarasin
ORCID	Author(s) ORCID Number Wachira Wongtanasarasin http://orcid.org/0000-0002-1418-0036
Funding Agency and Grant Number
Corresponding Author	Wachira Wongtanasarasin, MD, Assistant Professor, Department of Emergency Medicine, Faculty of Medicine, Chiang Mai University, 110 Intavarorot Street, Sriphum, Chiang Mai 50200, Thailand. wachir_w@hotmail.com
Key Words	COVID-19; Cholestatic injury; Cholangiopathy; Alkaline phosphatase
Core Tip	The 2019 coronavirus disease (COVID-19) is not only regarded as a respiratory tract disease but also demonstrates a wide range of systemic consequences, including the biliary tract. A significant increase in serum alkaline phosphatase and signs of biliary injury on imaging and/or pathology are the hallmarks of COVID-19-associated cholangiopathy. Direct viral invasion, ischemic injury related to microvascular coagulopathy, drug-induced cholestatic liver injury, alteration of gut microbiota, and cytokine release syndrome are proposed as potential explanations for cholangiopathy associated with severe COVID-19 infection.
Publish Date	2022-11-23 13:56
Citation	Wongtanasarasin W. Cholestatic liver injury: A rare but fatal complication during and after COVID-19 infection. World J Virol 2022; 11(6): 435-442
URL	https://www.wjgnet.com/2220-3249/full/v11/i6/435.htm
DOI	https://dx.doi.org/10.5501/wjv.v11.i6.435

Full Article (PDF)	WJV-11-435.pdf
Full Article (Word)	WJV-11-435.docx
Manuscript File	79220_Auto_Edited-LM_WangTQ.docx
Answering Reviewers	79220-Answering reviewers.pdf
Audio Core Tip	79220-Audio core tip.mov
Conflict-of-Interest Disclosure Form	79220-Conflict-of-interest statement.pdf
Copyright License Agreement	79220-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	79220-Language certificate.pdf
Supplementary Material	79220-Supplementary material.pdf
Peer-review Report	79220-Peer-review(s).pdf
Scientific Misconduct Check	79220-Bing-Chen YL-2.png
Scientific Editor Work List	79220-Scientific editor work list.pdf
CrossCheck Report	79220-CrossCheck report.pdf