Publication Name	World Journal of Diabetes
Manuscript ID	7923
Country	Italy

Received	2013-12-06 21:51
Peer-Review Started	2013-12-08 14:11
To Make the First Decision	2013-12-25 18:02
Return for Revision	2013-12-27 08:47
Revised	2014-01-18 02:00
Second Decision	2014-04-11 18:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-11 19:05
Articles in Press	2014-05-23 09:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-13 20:59
Publish the Manuscript Online	2014-06-16 15:44

ISSN	1948-9358 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Anesthesiology
Manuscript Type	Editorial
Article Title	Short acting insulin analogues in intensive care unit patients
Manuscript Source	Invited Manuscript
All Author List	Federico Bilotta, Carolina Guerra, Rafael Badenes, Simona Lolli and Giovanni Rosa
Funding Agency and Grant Number
Corresponding Author	Federico Bilotta, MD, Department of Anesthesiology and Intensive Care, Section of Neurosurgery, “Sapienza” University of Rome, Piazzale Aldo Moro, 5, 00185 Roma, Italy. bilotta@tisscali.it
Key Words	Insulin analogues; Short acting drugs; Intensive insulin therapy; Glycemia management; Intensive care
Core Tip	In this article we report the rationale of using short acting drugs in intensive care unit (ICU) patients (i.e., sedation and treatment of arterial hypertension) and we also describe short acting insulin analogues (SAIA) and their pharmacokinetic (PK) and pharmacodynamic profile. SAIA have been synthesized to improve the chronic treatment of patients with diabetes but, because of the PK characteristics that include shorter onset and offset, they can be effectively used also in ICU patients and have the potential to be associated with a more limited risk of inducing episodes of iatrogenic hypoglycemia.
Publish Date	2014-06-16 15:44
Citation	Bilotta F, Guerra C, Badenes R, Lolli S, Rosa G. Short acting insulin analogues in intensive care unit patients. World J Diabetes 2014; 5(3): 230-234
URL	http://www.wjgnet.com/1948-9358/full/v5/i3/230.htm
DOI	http://dx.doi.org/10.4239/wjd.v5.i3.230

Full Article (PDF)	WJD-5-230.pdf
Full Article (Word)	WJD-5-230.doc
Manuscript File	7923-Review.doc
Answering Reviewers	7923-Answering reviewers.pdf
Copyright License Agreement	7923-Copyright assignment.pdf
Peer-review Report	7923-Peer review(s).pdf
Scientific Editor Work List	7923-Scientific editor work list.doc