| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Atypical Whipple’s disease with special endoscopic manifestations: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shuo Chen, Yuan-Chen Zhou, Shuang Si, Hong-Yan Liu, Qing-Rui Zhang, Teng-Fei Yin, Chu-Xi Xie, Shu-Kun Yao and Shi-Yu Du |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The China-Japan Friendship Hospital Foundation |
No. 2019-1-QN-2 |
|
| Corresponding Author |
Shi-Yu Du, MD, PhD, Chief Physician, Professor, Department of Gastroenterology, China-Japan Friendship Hospital, No. 2 Yinghua East Road, Chaoyang District, Beijing 100029, China. shiyudu1975@163.com |
| Key Words |
Whipple’s disease; Whipple operation; Endoscopy; Tropheryma whipplei; PAS staining; Intestinal polyposis; Case report |
| Core Tip |
Whipple’s disease is a rare disease diagnosed by invasive manipulation. We reported on the case of a 58-year-old male patient who complained of fatigue and decreased exercise capacity. Results of gastroscopy and capsule endoscopy showed multiple polypoid bulges distributed in the duodenal and proximal jejunum. A diagnosis of small intestinal adenomatosis was initially considered; hence, the Whipple procedure, a pylorus-preserving pancreaticoduodenectomy, was performed. Many polyglandular autoimmune syndromes-positive macrophages aggregated in the intestinal mucosa of the duodenum, upper jejunum, and surrounding lymph nodes. Based on comprehensive analysis of symptoms, laboratory findings, and pathological manifestations, the patient was finally diagnosed with Whipple’s disease. |
| Publish Date |
2022-12-14 07:20 |
| Citation |
Chen S, Zhou YC, Si S, Liu HY, Zhang QR, Yin TF, Xie CX, Yao SK, Du SY. Atypical Whipple’s disease with special endoscopic manifestations: A case report. World J Clin Cases 2022; 10(35): 13044-13051 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i35/13044.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i35.13044 |
