Publication Name	World Journal of Gastroenterology
Manuscript ID	7943
Country	China

Received	2013-12-08 11:38
Peer-Review Started	2013-12-08 15:50
To Make the First Decision	2014-02-14 18:22
Return for Revision	2014-02-18 20:57
Revised	2014-03-10 23:15
Second Decision	2014-04-09 09:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-09 11:04
Articles in Press	2014-05-23 10:48
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-01 19:39
Typeset the Manuscript	2014-06-20 14:37
Publish the Manuscript Online	2014-07-03 15:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Effect of a high-fat diet in development of colonic adenoma in an animal model
Manuscript Source	Invited Manuscript
All Author List	Qing-Chao Zhu, Ren-Yuan Gao, Wen Wu, Bo-Min Guo, Jia-Yuan Peng and Huan-Long Qin
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81230057
Corresponding Author	Huan-Long Qin, MD, PhD, Department of Surgery, the Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, 600 Yishan Road, Shanghai 200233, China. huanlongqin@yahoo.com
Key Words	High-fat diet; Colonic adenomas; Inflammation; Adipokines
Core Tip	This study was undertaken to explore the effect of a high-fat diet on the incidence of colonic adenoma induced by intraperitoneal injection of 1,2-dimethylhydrazine in Wistar rats. We demonstrated that a high-fat diet (HFD) increased the proliferative activity of colonic epithelial cells, and we conclude that HFD-mediated tumor growth could be associated with inflammation and increased cell cycle progression. This study might be conducive to understanding the nature of the relationship between high fat intake and the increased risk of colorectal carcinoma.
Publish Date	2014-07-03 15:30
Citation	Zhu QC, Gao RY, Wu W, Guo BM, Peng JY, Qin HL. Effect of a high-fat diet in the development of colonic adenoma in an animal model. World J Gastroenterol 2014; 20(25): 8119-8129
URL	http://www.wjgnet.com/1007-9327/full/v20/i25/8119.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i25.8119

Full Article (PDF)	WJG-20-8119.pdf
Full Article (Word)	WJG-20-8119.doc
Manuscript File	7943-Review.doc
Answering Reviewers	7943-Answering reviewers.pdf
Copyright License Agreement	7943-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7943-Language certificate.pdf
Peer-review Report	7943-Peer review.pdf
Scientific Editor Work List	7943-Scientific editor work list.doc