11/16/2022 11:26:06 AM | Browse: 427 | Download: 1056
| Publication Name | World Journal of Gastroenterology |
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| Manuscript ID | 79530 |
| Country | China |
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| ISSN | 1007-9327 (print) and 2219-2840 (online) |
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| Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright | ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Gastroenterology & Hepatology | ||||||||
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| Manuscript Type | Basic Study | ||||||||
| Article Title | Salvia miltiorrhiza extract may exert an anti-obesity effect in rats with high-fat diet-induced obesity by modulating gut microbiome and lipid metabolism | ||||||||
| Manuscript Source | Unsolicited Manuscript | ||||||||
| All Author List | Zi-Li Ai, Xian Zhang, Wei Ge, You-Bao Zhong, Hai-Yan Wang, Zheng-Yun Zuo and Duan-Yong Liu | ||||||||
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| Corresponding Author | Hai-Yan Wang, PhD, Associate Professor, Formula-Pattern Research Center, Jiangxi University of Chinese Medicine, No. 1688 Meiling Road, Nanchang 330004, Jiangxi Province, China. 378278287@qq.com | ||||||||
| Key Words | Salvia miltiorrhiza extract; Obesity; Gut microbiota; Lipid metabolism; High fat diet | ||||||||
| Core Tip | Obesity is a major public health issue today and an obesity-related change in gut microbiota composition and its metabolite profile has been demonstrated. As a commonly used traditional Chinese medicine, Salvia miltiorrhiza extract (Sal) has many pharmacological effects, including anticoagulant, anti-inflammation, antioxidation, anti-fibrosis, anti-tumor, and organ protection. Although it has not been documented, Sal has a regulatory effect on obesity, which may be related to the gut microbiota. In the present study, we found that Sal plays a role in weight loss, lowering serum lipid levels, regulating the gut microbiota, and improving intestinal fecal metabolites in obese rats. | ||||||||
| Publish Date | 2022-11-16 11:26 | ||||||||
| Citation | Ai ZL, Zhang X, Ge W, Zhong YB, Wang HY, Zuo ZY, Liu DY. Salvia miltiorrhiza extract may exert an anti-obesity effect in rats with high-fat diet-induced obesity by modulating gut microbiome and lipid metabolism. World J Gastroenterol 2022; 28(43): 6131-6156 | ||||||||
| URL | https://www.wjgnet.com/1007-9327/full/v28/i43/6131.htm | ||||||||
| DOI | https://dx.doi.org/10.3748/wjg.v28.i43.6131 |
| Full Article (PDF) | WJG-28-6131.pdf |
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| Full Article (Word) | WJG-28-6131.docx |
| The ARRIVE Guidelines | 79530-The-ARRIVE-Guidelines-revision.pdf |
| Manuscript File | 79530_Auto_Edited-LM.docx |
| Answering Reviewers | 79530-Answering reviewers.pdf |
| Audio Core Tip | 79530-Audio core tip.mp3 |
| Biostatistics Review Certificate | 79530-Biostatistics statement.pdf |
| Conflict-of-Interest Disclosure Form | 79530-Conflict-of-interest statement.pdf |
| Copyright License Agreement | 79530-Copyright license agreement.pdf |
| Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) | 79530-Grant application form(s).pdf |
| Institutional Animal Care and Use Committee Approval Form or Document | 79530-Institutional animal care and use committee statement.PDF |
| Non-Native Speakers of English Editing Certificate | 79530-Language certificate.pdf |
| Peer-review Report | 79530-Peer-review(s).pdf |
| Scientific Misconduct Check | 79530-Bing-Chen YL-2.png |
| Scientific Editor Work List | 79530-Scientific editor work list.pdf |
| CrossCheck Report | 79530-CrossCheck report.pdf |