Publication Name	World Journal of Orthopedics
Manuscript ID	79620
Country	Greece

Received	2022-08-29 19:03
Peer-Review Started	2022-08-29 19:07
To Make the First Decision
Return for Revision	2022-09-26 10:34
Revised	2022-10-09 01:01
Second Decision	2022-10-14 03:17
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-10-14 18:34
Articles in Press	2022-10-14 18:34
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-11-01 02:01
Typeset the Manuscript	2022-11-13 22:35
Publish the Manuscript Online	2022-11-16 11:29

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the yoriginal work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Editorial
Article Title	Genetics in congenital anomalies of the hand
Manuscript Source	Invited Manuscript
All Author List	Zisis Kyriazis, Panagoula Kollia, Ioanna Grivea, Sotirios Sotiriou and Zoe H Dailiana
ORCID	Author(s) ORCID Number Zisis Kyriazis http://orcid.org/0000-0003-2465-8774 Panagoula Kollia http://orcid.org/0000-0002-0635-3996 Ioanna Grivea http://orcid.org/0000-0002-9221-5628 Sotirios Sotiriou http://orcid.org/0000-0002-9466-6086 Zoe H Dailiana http://orcid.org/0000-0003-3890-0832
Funding Agency and Grant Number
Corresponding Author	Zoe H Dailiana, MD, PhD, Professor, Surgeon, Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, No. 3 Panepistimiou Street, Biopolis , Larissa 41500, Greece. dailiana@med.uth.gr
Key Words	Hand; Gene; Mutation; Molecular; Diagnosis; Disorders
Core Tip	The genetic basis of hand disorders is elucidated by the expansion of knowledge and introduction of molecular analysis techniques which contribute to the identification of new genes responsible for them. New genes and mutations are being isolated and correlated with the disorder based on the advances in sequencing technology, such as next generation sequencing and genetic consultation and future therapeutic developments are enhanced. There appears to be a gap in the literature concerning the knowledge about the genetic basis of all hand disorders. The current molecular status of them is discussed and a summary of different genes, already identified or suspected to be related with them is presented.
Publish Date	2022-11-16 11:29
Citation	Kyriazis Z, Kollia P, Grivea I, Sotiriou S, Dailiana ZH. Genetics of congenital anomalies of the hand. World J Orthop 2022; 13(11): 949-954
URL	https://www.wjgnet.com/2218-5836/full/v13/i11/949.htm
DOI	https://dx.doi.org/10.5312/wjo.v13.i11.949

Full Article (PDF)	WJO-13-949.pdf
Full Article (Word)	WJO-13-949.docx
Manuscript File	79620_Auto_Edited-LM_WangTQ.docx
Answering Reviewers	79620-Answering reviewers.pdf
Audio Core Tip	79620-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	79620-Conflict-of-interest statement.pdf
Copyright License Agreement	79620-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	79620-Language certificate.pdf
Peer-review Report	79620-Peer-review(s).pdf
Scientific Misconduct Check	79620-Bing-Wang LL-2.png
Scientific Editor Work List	79620-Scientific editor work list.pdf
CrossCheck Report	79620-CrossCheck report.pdf