11/25/2022 9:29:01 AM | Browse: 393 | Download: 996
| Publication Name | World Journal of Gastrointestinal Surgery |
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| Manuscript ID | 79695 |
| Country | China |
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| ISSN | 1948-9366 (online) |
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| Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright | ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Gastroenterology & Hepatology | ||||||||||||||
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| Manuscript Type | Retrospective Study | ||||||||||||||
| Article Title | Recombinant human thrombopoietin treatment in patients with chronic liver disease-related thrombocytopenia undergoing invasive procedures: A retrospective study | ||||||||||||||
| Manuscript Source | Unsolicited Manuscript | ||||||||||||||
| All Author List | Jing-Nuo Ding, Ting-Ting Feng, Wei Sun, Xin-Yi Cai, Yun Zhang and Wei-Feng Zhao | ||||||||||||||
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| Corresponding Author | Wei-Feng Zhao, MD, Chief Physician, Department of Infectious Diseases, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Gusu District, Suzhou 215000, Jiangsu Province, China. zhaoweifeng@suda.edu.cn | ||||||||||||||
| Key Words | Recombinant human thrombopoietin; Invasive procedures; Chronic liver disease; Liver cirrhosis; Thrombocytopenia; Platelet transfusion | ||||||||||||||
| Core Tip | Recombinant human thrombopoietin (rhTPO), commonly used to treat primary immune thrombocytopenic purpura and thrombocytopenia caused by solid tumor chemotherapy, has not been extensively investigated in the treatment of chronic liver disease (CLD)-related thrombocytopenia, where there is an increased risk of bleeding and a poor prognosis, especially in patients undergoing invasive procedures or surgery. Our retrospective study evaluates the efficacy of rhTPO in the treatment of patients with CLD-associated thrombocytopenia undergoing invasive procedures. Overall, rhTPO demonstrated good clinical efficacy by improving platelet count, reducing bleeding risk, decreasing the platelet transfusion rate, promoting the probability of tolerance to receive invasive management, and improving overall survival of patients with CLD. | ||||||||||||||
| Publish Date | 2022-11-25 09:29 | ||||||||||||||
| Citation | Ding JN, Feng TT, Sun W, Cai XY, Zhang Y, Zhao WF. Recombinant human thrombopoietin treatment in patients with chronic liver disease-related thrombocytopenia undergoing invasive procedures: A retrospective study. World J Gastrointest Surg 2022; 14(11): 1260-1271 | ||||||||||||||
| URL | https://www.wjgnet.com/1948-9366/full/v14/i11/1260.htm | ||||||||||||||
| DOI | https://dx.doi.org/10.4240/wjgs.v14.i11.1260 |
| Full Article (PDF) | WJGS-14-1260.pdf |
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| Full Article (Word) | WJGS-14-1260.docx |
| Manuscript File | 79695-Manuscript-File-revision.docx |
| Answering Reviewers | 79695-Answering reviewers.pdf |
| Audio Core Tip | 79695-Audio core tip.m4a |
| Biostatistics Review Certificate | 79695-Biostatistics statement.pdf |
| Conflict-of-Interest Disclosure Form | 79695-Conflict-of-interest statement.pdf |
| Copyright License Agreement | 79695-Copyright license agreement.pdf |
| Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) | 79695-Grant application form(s).pdf |
| Institutional Review Board Approval Form or Document | 79695-Institutional review board statement.pdf |
| Non-Native Speakers of English Editing Certificate | 79695-Language certificate.pdf |
| Peer-review Report | 79695-Peer-review(s).pdf |
| Scientific Editor Work List | 79695-Scientific editor work list.pdf |
| CrossCheck Report | 79695-CrossCheck report.pdf |