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Articles Published Processes
12/2/2022 12:50:19 PM | Browse: 546 | Download: 1336
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Received |
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2022-09-07 05:09 |
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Peer-Review Started |
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2022-09-07 05:11 |
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First Decision by Editorial Office Director |
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2022-10-20 18:15 |
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Return for Revision |
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2022-10-21 02:04 |
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Revised |
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2022-10-25 16:03 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-11-04 03:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-11-04 08:47 |
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Articles in Press |
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2022-11-04 08:47 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-11-07 08:46 |
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Publish the Manuscript Online |
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2022-12-02 12:50 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Evaluation of gut dysbiosis using serum and fecal bile acid profiles
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Tadakuni Monma, Junichi Iwamoto, Hajime Ueda, Makoto Tamamushi, Fumio Kakizaki, Naoki Konishi, Shoichiro Yara, Teruo Miyazaki, Takeshi Hirayama, Tadashi Ikegami and Akira Honda |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Junichi Iwamoto, MD, PhD, Professor, Department of Gastroenterology and Hepatology, Tokyo Medical University Ibaraki Medical Center, 3-20-1, Amimachi-Chuo, Inashiki-Gun 300-0395, Japan. iwamotoj@tokyo-med.ac.jp |
| Key Words |
Gut dysbiosis; Clostridium subcluster XIVa; Bile acids; HPLC-MS/MS; Inflammatory bowel diseases; Clostridium difficile infection |
| Core Tip |
Gut dysbiosis, particularly decreased XIVa, correlates strongly with decreased conversion of primary BAs to secondary BAs. Decreased levels of Clostridium subcluster XIVa (XIVa) are associated with the intestinal dysbiosis found in inflammatory bowel disease (IBD) and Clostridium difficile infection (CDI). Since XIVa is a bacterial group responsible for the conversion of primary BAs to secondary BAs, the proportion of intestinal XIVa can be predicted by determining the ratio of deoxycholic acid (DCA)/ [DCA + cholic acid (CA)] in feces or serum. Therefore, the DCA/(DCA+CA) ratio in feces and serum is a valuable marker for detecting dysbiosis without genetic analysis of enterobacteria. |
| Publish Date |
2022-12-02 12:50 |
| Citation |
Monma T, Iwamoto J, Ueda H, Tamamushi M, Kakizaki F, Konishi N, Yara S, Miyazaki T, Hirayama T, Ikegami T, Honda A. Evaluation of gut dysbiosis using serum and fecal bile acid profiles. World J Clin Cases 2022; 10(34):12484-12493 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i34/12484.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i34.12484 |
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