Publication Name	World Journal of Gastroenterology
Manuscript ID	79864
Country	Japan

Received	2022-09-09 15:31
Peer-Review Started	2022-09-09 15:34
First Decision by Editorial Office Director	2022-09-29 21:25
Return for Revision	2022-09-29 21:25
Revised	2022-10-24 15:26
Publication Fee Transferred
Second Decision by Editor	2022-11-08 03:12
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2022-11-09 13:51
Articles in Press	2022-11-09 13:51
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-11-21 07:48
Publish the Manuscript Online	2022-11-25 02:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Microbiology
Manuscript Type	Minireviews
Article Title	Development of Epstein-Barr virus-associated gastric cancer: infection, inflammation, and oncogenesis
Manuscript Source	Invited Manuscript
All Author List	Hisashi Iizasa, Andi Visi Kartika, Sintayehu Fekadu, Shunpei Okada, Daichi Onomura, Afifah Fatimah Azzahra Ahmad Wadi, Mosammat Mahmuda Khatun, Thin Myat Moe, Jun Nishikawa and Hironori Yoshiyama
ORCID	Author(s) ORCID Number Jun Nishikawa http://orcid.org/0000-0002-6695-9754 Hironori Yoshiyama http://orcid.org/0000-0001-7588-278X
Funding Agency and Grant Number	Funding Agency Grant Number Grant-in-Aid for Scientific Research From the Ministry of Education, Culture, Science and Technology of Japan 21K07054 (Hironori Yoshiyama) Grant-in-Aid for Scientific Research From the Ministry of Education, Culture, Science and Technology of Japan 22K07101 (Hisashi Iizasa)
Corresponding Author	Hironori Yoshiyama, MD, PhD, Professor, Department of Microbiology, Shimane University Faculty of Medicine, 89-1 Enyacho, Izumo 693-8501, Shimane, Japan. yosiyama@med.shimane-u.ac.jp
Key Words	Helicobacter pylori; Epstein-Barr virus; Epstein-Barr virus-associated gastric cancer; Coreceptor; Inflammation; Oncogenesis
Core Tip	Epstein-Barr virus (EBV)-associated gastric cancer (EBVaGC) tumor cells originate from a single cell clone infected with EBV. In contrast, it is reported that more than 95% of patients with gastric cancer have a history of Helicobacter pylori (H. pylori) infection. Accordingly, it has long been argued that H. pylori infection may have some effect on the development of EBVaGC, a subtype of gastric cancer. It is also a mystery that the number of gastric cancer patients is higher in Asia, South America, and the Middle East. We will reorganize the role of H. pylori and EBV infections in gastric cancer formation.
Publish Date	2022-11-25 02:19
Citation	Iizasa H, Kartika AV, Fekadu S, Okada S, Onomura D, Wadi AFAA, Khatun MM, Moe TM, Nishikawa J, Yoshiyama H. Development of Epstein-Barr virus-associated gastric cancer: infection, inflammation, and oncogenesis. World J Gastroenterol 2022; 28(44): 6249-6257
URL	https://www.wjgnet.com/1007-9327/full/v28/i44/6249.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i44.6249

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